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Distinction of white, beige and brown adipocytes derived from mesenchymal stem cells
Anna Park, Won Kon Kim, Kwang-Hee Bae
Anna Park, Won Kon Kim, Kwang-Hee Bae, Research Center for Integrated Cellulomics, KRIBB, Daejeon 305-806, South Korea
Anna Park, Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, South Korea
Author contributions: Bae KH substantially contributed to the concept of the review; Park A and Kim WK finalized the text, designed the images, performed the image acquisition and contributed equally to this work.
Supported by Grants from the National Research of Foundation of the South Korea, No. 2012M3A9C7050101, No. 2011-0030028 and No. 2006-2004112
Correspondence to: Kwang-Hee Bae, PhD, Director, Research Center for Integrated Cellulomics, KRIBB, Daejeon 305-806, South Korea. email@example.com
Telephone: +82-42-8604268 Fax: +82-42-8604269
Received: October 25, 2013 Revised: December 5, 2013 Accepted: January 6, 2014 Published online: January 26, 2014
Core tip: Here, we summarize the characteristic differences of the white, brown and beige adipocytes derived from mesenchymal stem cells, including their anatomical location. In particular, we focus on the newly discovered brown-like adipocytes called beige/brite adipocytes. A deeper understanding of the molecular mechanism of these adipocytes may provide clues for overcoming obesity and its associated metabolic diseases.