Cardiac differentiation is modulated by anti-apoptotic signals in murine embryonic stem cells
Amani Yehya, Joseph Azar, Mohamad Al-Fares, Helene Boeuf, Wassim Abou-Kheir, Dana Zeineddine, Ola Hadadeh
Amani Yehya, Joseph Azar, Mohamad Al-Fares, Wassim Abou-Kheir, Ola Hadadeh, Department of Anatomy, Cell Biology and Physiological Sciences, American University of Beirut, Beirut 1107-2020, Lebanon
Helene Boeuf, Inserm, Biotis, U1026, University Bordeaux, Bordeaux F-33000, France
Dana Zeineddine, Rammal Rammal Lab, Physio-Toxicity Environmental Team, Faculty of Sciences, Lebanese University, Nabatieh 0000, Lebanon
Co-first authors: Amani Yehya and Joseph Azar.
Co-corresponding authors: Dana Zeineddine and Ola Hadadeh.
Author contributions: Yehya A and Azar J contributed equally to this work as co-first authors, and they wrote the manuscript and performed data analysis and interpretation; Al-Fares M performed initial lab work and participated in data collection; Boeuf H provided the genetically manipulated cell lines employed in this study; Abou-Kheir W, Zeineddine D, and Hadadeh O contributed as co-senior authors, and they conceived the project, managed and supervised the work, discussed the data, acquired the reagents, and corrected the manuscript draft; Zeineddine D and Hadadeh O contributed as co-corresponding authors, and they acquired the funding and reagents; and all authors have reviewed and approved the final manuscript.
Supported by the National Council for Scientific Research in Lebanon, CNRS-L.
Institutional review board statement: This is to confirm that no patient samples were used in this research study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Ola Hadadeh, PhD, Associate Research Scientist, Department of Anatomy, Cell Biology and Physiological Sciences, American University of Beirut, Bliss Street-Hamra, Beirut 1107-2020, Lebanon. hadadeh.ola@gmail.com
Received: December 30, 2023
Revised: January 29, 2024
Accepted: April 1, 2024
Published online: May 26, 2024
Processing time: 145 Days and 10.2 Hours
