Review
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stem Cells. Jun 26, 2021; 13(6): 568-593
Published online Jun 26, 2021. doi: 10.4252/wjsc.v13.i6.568
Review of the potential of mesenchymal stem cells for the treatment of infectious diseases
Amit Sharma, Anuja Chakraborty, Bithiah Grace Jaganathan
Amit Sharma, Anuja Chakraborty, Bithiah Grace Jaganathan, Stem Cell and Cancer Biology Group, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, India
Author contributions: Sharma A wrote the manuscript; Chakraborty A wrote the manuscript; Jaganathan BG conceptualized the study and wrote the manuscript; All authors have read and approved the final version of the manuscript.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bithiah Grace Jaganathan, PhD, Associate Professor, Stem Cell and Cancer Biology Group, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Amingaon, Guwahati 781039, Assam, India. bithiahgj@iitg.ac.in
Received: March 8, 2021
Peer-review started: March 8, 2021
First decision: March 29, 2021
Revised: April 7, 2021
Accepted: June 3, 2021
Article in press: June 3, 2021
Published online: June 26, 2021
Processing time: 110 Days and 0.1 Hours
Core Tip

Core Tip: This review discusses the therapeutic benefits of utilizing mesenchymal stem cells (MSCs) to treat infectious diseases and repair tissue damage induced by the disease-causing infectious agents. The immunomodulatory and regenerative properties of MSCs are modulated by the inflammatory milieu generated by the disease and should be considered while utilizing MSCs for treatment.