Improvements of postburn renal function by early enteral feeding and their possible mechanisms in rats

Table 1 Effects of EEF on postburn changes of BUN, BCr and CCr (¯x ± s)

Group	Samples	Postbun hours (h)
		3	6	12	24	48
EEF	40
BUN (mmol/L)		10.30 ± 0.67ad	17.67 ± 1.52bd	13.73 ± 1.43d	8.73 ± 2.10d	7.50 ± 1.16d
BCr (mmol/L)		53.77 ± 3.20d	89.60 ± 6.54bd	55.44 ± 3.57d	46.95 ± 2.66d	42.90 ± 2.23d
CCr (ml/h/100g)					16.43 ± 2.90 b
Burn	40
BUN (mmol/L)		11.76 ± 1.72d	15.42 ± 1.74d	13.48 ± 1.56d	9.27 ± 1.75d	7.68 ± 1.63d
BCr (mmol/L)		51.80 ± 2.83d	71.23 ± 2.63d	57.70 ± 4.93d	44.75 ± 1.69d	41.76 ± 1.26d
CCr (ml/h/100g)					3.52 ± 0.79d
Control	40
BUN (mmol/L)		4.67 ± 0.85	4.49 ± 0.58	4.74 ± 0.80	4.31 ± 0.69	4.52 ± 0.93
BCr (mmol/L)		37.43 ± 3.64	37.67 ± 3.26	37.28 ± 4.42	36.94 ± 3.71	37.69 ± 3. 47
CCr (ml/h/100g)					19.45 ± 2.21

^aP < 0.05,

^bP < 0.01 vs Burn group; ^cP < 0.05,

^dP < 0.01 vs Control.

Table 2 Effects of EEF on postburn changes of gastric intramucosal pH(¯x ± s)

Group	Samples	Postbun hours (h)
		3	6	12	24	48
EEF	50	7.119 ± 0.078ab	6.943 ± 0.089ab	7.074 ± 0.037ab	7.285 ± 0.098a	7.257 ± 0.077ab
Burn	50	7.017 ± 0.037b	6.826 ± 0.049b	6.802 ± 0.080b	6.949 ± 0.082b	7.074 ± 0.041b
Control	50	7.321 ± 0.054	7.296 ± 0.067	7.343 ± 0.045	7.306 ± 0.069	7.348 ± 0.074

^aP < 0.01 vs Burn group;

^bP < 0.01 vs Control.

Table 3 Effects of EEF on postburn changes of portal endotoxin level (Eu/ml, ¯x ± s)

Group	Samples	Postbun hours (h)
		3	6	12	24	48
EEF	40	0.683 ± 0.072ab	0.797 ± 0.085ab	0.542 ± 0.078ab	0.725 ± 0.061ab	0.461 ± 0.049ab
Burn	40	1.394 ± 0.126b	1.518 ± 0.173b	1.124 ± 0.133b	1.627 ± 0.215b	1.168 ± 0.188b
Control	40	0.206 ± 0.032	0.195 ± 0.043	0.189 ± 0.049	0.204 ± 0.037	0.215 ± 0.051

^aP < 0.01 vs Burn group;

^bP < 0.01 vs Control.

Table 4 Effects of EEF on postburn changes of plasma TNF-α level (ng/ml, ¯x ± s)

Group	Samples	Postbun hours (h)
		3	6	12	24	48
EEF	40	1.48 ± 0.38ab	2.57 ± 0.45ab	2.36 ± 0.47ab	1.92 ± 0.26ab	1.68 ± 0.45ab
Burn	40	1.92 ± 0.19b	4.49 ± 0.47b	3.51 ± 0.45b	4.07 ± 0.71b	3.24 ± 0.61b
Control	40	0.83 ± 0.08	0.78 ± 0.11	0.83 ± 0.12	0.81 ± 0.09	0.85 ± 0.10

^aP < 0.01 vs Burn group;

^bP < 0.01 vs Control.