Changes of integrin expression in rat hepatocarcinogenesis induced by 3&rsquo;-Me-DAB

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Apr 15, 2000 (publication date) through Jul 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 15, 2000; 6(2): 231-233
Published online Apr 15, 2000. doi: 10.3748/wjg.v6.i2.231

Table 1 Pattern of integrins and EK in normal liver, liver cirrhosis and liver tumor

	α₁	α₂	α₃	α₅	EK
Normal liver tissue
Hepatocytes	+	-	-	+	-
Sinusoidal endothelial cells	+	-	-	+	-
Bile duct epithelium	-	-	-	-	+++
Liver cirrhosis
Hepatocytes	+++	++	++	+++	-
Sinusoidal endothelial cells	++	+	+	++	-
Oval cell	+/-	+/-	+/-	+/-	+++/-
Hyperplastic bile duct epithelium	++	-	-	++	+++
Preneoplastic nodules	+	+/-	+/-	+	-
Tumor
Primary	-/+	-	-	-/+	+++/-
Metastasis	+++/-	-	-	+++/-	+++/-

Citation: Yuan ST, Hu XQ, Lu JP, KeiKi H, Zhai WR, Zhang YE. Changes of integrin expression in rat hepatocarcinogenesis induced by 3’-Me-DAB. World J Gastroenterol 2000; 6(2): 231-233
URL: https://www.wjgnet.com/1007-9327/full/v6/i2/231.htm
DOI: https://dx.doi.org/10.3748/wjg.v6.i2.231