Effects of Fuzhenghuayu decoction on collagen synthesis of cultured hepatic stellate cells, hepatocytes and fibroblasts in rats

Table 1 Effects of drug sera on HSC collagen synthesis rate (n = 4, % x^-±s)

Group	Normal subcultured HSC		Fibrotic HSC
	Intracellular	Extracellular	Intracellular	Extracellular
Drug sera	0.31 ± 0.21	2.70 ± 0.10a	0.12 ± 0.09a	0.80 ± 0.34b
Control	0.57 ± 0.37	4.15 ± 0.95	0.33 ± 0.10	1.72 ± 0.53

^aP < 0.05,

^bP < 0.01, vs control.

Table 2 Effects of drug sera on hepatocyte collagen synthesis rate (n = 4, % x^-±s)

Group	Normal subcultured HSC		Fibrotic HSC
	Intracellular	Extracellular	Intracellular	Extracellular
Drug sera	0.34 ± 0.05	0.23 ± 0.04a	0.84 ± 0.16a	0.43 ± 0.12b
Control	0.31 ± 0.09	0.30 ± 0.02	1.24 ± 0.50	0.60 ± 0.14

^aP < 0.05,

^bP < 0.01, vs Control.

Table 3 Effects of drug sera on NIH/3T3 fibroblast collagen synthesis rate (n = 4, % x^-±s)

Group	Intracellular	Extracellular
Drug sera	1.53 ± 0.50 (6)	8.89 ± 3.66 (6)
Control	2.03 ± 0.75 (5)	12.62 ± 1.03 (4)

In bracket was the case numbers.