Effect of devazepide reversed antagonism of CCK-8 against morphine on electrical and mechanical activities of rat duodenum in vitro

Table 1 Anti-morphine effect of CCK-8 reversed by Devazepide

Items	Control	Ach	Morphine	CCK-8	Devazepide
	n = 22	300 nmol/L	330 nmol/L	0.7 nmol/L	10 nmol/L
	(0 s)	(60 s)	(120 s)	(240 s)	(325 s)
SPA (mV)	0.70 ± 0.07	0.94 ± 0.09b	0.59 ± 0.06d	0.81 ± 0.07f	0.54 ± 0.05h
SPN	2.71 ± 0.23	3.88 ± 0.15b	2.71 ± 0.09d	3.52 ± 0.13f	2.66 ± 0.18h
CA (mm)	16.40 ± 1.00	24.44 ± 1.63b	13.54 ± 1.04d	22.73 ± 1.00f	13.67 ± 0.66h

^bP < 0.01 (ACh vs control);

^dP < 0.01 (morphine vs ACh);

^fP < 0.01 (CCK-8 vs morphine);

^hP < 0.01 (Devazepide vs CCK-8).