Protective effect of YHI and HHI-I against experimental acute pancreatitis in rabbits

Table 1 The effect of YHI and HHI-I on serum amylase of rabbit with SAP (x^-±s)

Group	Before AP	After AP (d)
		1	3	5
Treatment (U/L)	867.67 ± 374.62	6320.83 ± 2614.12(6)b	4774.0 ± 1859.36(5)b	1596.6 ± 760.50(5)
Control (U/L)	838.17 ± 189.12	7586.67 ± 3745.03(5)b	7380.0 ± 3687.41(4)b	2095.0 ± 1081.87(2)a

( ) number of survived,

^aP < 0.05 and

^bP < 0.01 compared with before AP.

Table 2 The effect of YHI and HHI-I on serum interleukin-6 in AP rabbits (x^-±s)

Group	Before AP	After AP (d)
		1	3	5
Control (U/L)	32.37 ± 9.11(6)	69.75 ± 19.18(5)	72.35 ± 10.14(4)	70.25 ± 10.34(2)
Treatment (U/L)	30.0 ± 16.40(6)	59.50 ± 17.59(6)	50.33 ± 16.57(5)a	46.50 ± 14.94(5)a

( ): Animal number,

^aP < 0.05 compared with control.

Table 3 Effect of YHI and HHI-I on pathologic changes of pancreas in rabbits with SAP

	Control group	Treatment group
Lobule structure	Destroyed totally	Relatively intact
Acinus	Destroyed	Atrophied
Intralobular duct	Destroyed seriously	Existed, expanded
Interlobular duct	Residually existed	Existed
Fatty tissue	Destroyed totally	Mild-moderately destroyed
Inflammatory cell	Abscess formed	A few abscesses and WBC
Focal hemorrhage	Large size	Small size and a few number
Interstitial hyperplasia of fibrous tissue	A few around abscess and necrosis	Much more around abscess and necrosis
Island	No	Existed