Prognostic role of expression of angiogenesis markers in hepatocellular carcinoma: A bioinformatics analysis

Table 1 Detailed statistical results of differential expression analysis of angiogenesis markers in hepatocellular carcinoma

Gene	Group	Number	Minimum	Maximum	Median	IQR	Lower quartile	Upper quartile	Mean	SD	SE
ANGPT1	Normal	50	0.029	0.552	0.188	0.132	0.138	0.27	0.206	0.106	0.015
ANGPT1	Tumor	374	0	2.351	0.373	0.464	0.2	0.664	0.485	0.391	0.02
ANGPT2	Normal	50	0.043	1.351	0.278	0.33	0.195	0.525	0.394	0.289	0.041
ANGPT2	Tumor	374	0.116	3.339	0.848	0.769	0.513	1.282	0.963	0.581	0.03
VEGFA	Normal	50	1.616	3.901	2.687	0.473	2.439	2.911	2.717	0.445	0.063
VEGFA	Tumor	374	1.258	6.138	3.268	1.103	2.769	3.871	3.291	0.809	0.042
VEGFB	Normal	50	2.816	4.919	3.568	0.523	3.325	3.848	3.636	0.444	0.063
VEGFB	Tumor	374	0.978	8.003	4.532	2.234	3.223	5.458	4.292	1.521	0.079
VEGFC	Normal	50	0.408	1.901	1.019	0.453	0.787	1.239	1.057	0.355	0.05
VEGFC	Tumor	374	0.253	4.988	1.376	0.816	0.978	1.795	1.436	0.62	0.032
VEGFD	Normal	50	0.054	1.74	0.236	0.151	0.164	0.316	0.307	0.28	0.04
VEGFD	Tumor	374	0.014	6.756	0.422	0.622	0.241	0.863	0.838	1.14	0.059
PGF	Normal	50	0.182	0.992	0.471	0.204	0.37	0.575	0.501	0.188	0.027
PGF	Tumor	374	0.061	5.991	1.007	0.855	0.613	1.467	1.104	0.675	0.035
AFP	Normal	50	0.266	1.969	1.016	0.507	0.714	1.221	0.992	0.416	0.059
AFP	Tumor	374	0	13.118	1.644	2.855	0.844	3.699	2.965	3.15	0.163

ANGPT: Angiopoietin; VEGFA: Vascular endothelial growth factor; PGF: Placental growth factor; AFP: Alpha-fetoprotein; IQR: Interquartile range; SD: Standard deviation, SE: Standard error.

Table 2 Detailed statistical results of differential expression analysis of angiogenesis markers in paired samples of hepatocellular carcinoma

Gene	Group	Number	Minimum	Maximum	Median	IQR	Lower quartile	Upper quartile	Mean	SD	SE
ANGPT1	Normal	50	0.029	0.552	0.188	0.132	0.138	0.27	0.206	0.106	0.015
ANGPT1	Tumor	50	0.014	1.557	0.463	0.56	0.228	0.788	0.507	0.363	0.051
ANGPT2	Normal	50	0.043	1.351	0.278	0.33	0.195	0.525	0.394	0.289	0.041
ANGPT2	Tumor	50	0.193	2.324	1.056	0.77	0.747	1.517	1.111	0.517	0.073
VEGFA	Normal	50	1.616	3.901	2.687	0.473	2.439	2.911	2.717	0.445	0.063
VEGFA	Tumor	50	1.471	5.974	3.102	1.087	2.801	3.888	3.287	0.902	0.128
VEGFB	Normal	50	2.816	4.919	3.568	0.523	3.325	3.848	3.636	0.444	0.063
VEGFB	Tumor	50	1.164	7.789	4.833	1.993	3.323	5.317	4.328	1.575	0.223
VEGFC	Normal	50	0.408	1.901	1.019	0.453	0.787	1.239	1.057	0.355	0.05
VEGFC	Tumor	50	0.261	3.233	1.398	0.819	1.013	1.831	1.459	0.633	0.09
VEGFD	Normal	50	0.054	1.74	0.236	0.151	0.164	0.316	0.307	0.28	0.04
VEGFD	Tumor	50	0.014	5.746	0.367	0.562	0.231	0.793	0.832	1.207	0.171
PGF	Normal	50	0.182	0.992	0.471	0.204	0.37	0.575	0.501	0.188	0.027
PGF	Tumor	50	0.144	5.991	1.072	0.833	0.67	1.503	1.16	0.859	0.121
AFP	Normal	50	0.266	1.969	1.016	0.507	0.714	1.221	0.992	0.416	0.059
AFP	Tumor	50	0	5.824	1.033	1.31	0.725	2.036	1.62	1.383	0.196

ANGPT: Angiopoietin; VEGFA: Vascular endothelial growth factor; PGF: Placental growth factor; AFP: Alpha-fetoprotein; IQR: Interquartile range; SD: Standard deviation, SE: Standard error.