Effect of prolonged omeprazole administration on segmental intestinal Mg2+ absorption in male Sprague-Dawley rats

doi:10.3748/wjg.v26.i11.1142

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 21, 2020; 26(11): 1142-1155
Published online Mar 21, 2020. doi: 10.3748/wjg.v26.i11.1142

Table 1 Rate of total Mg²⁺ absorption, segmental length, and diameter of the duodenum, jejunum, ileum, and colon of the rats

	Rate of total Mg²⁺ transport		Level of suppression	Length (mm)[25]	Diameter (mm)[25]
	Control	24-wk omeprazole	Level of suppression	Length (mm)[25]	Diameter (mm)[25]
Duodenum	27.68 ± 1.36	5.02 ± 0.51	81.86%	95-100	2.5-3
Jejunum	31.01 ± 1.19	9.12 ± 0.75	70.59%	900-1350	4-5
Ileum	30.77 ± 0.94	9.40 ± 0.40	69.45%	25-35	3-5
Colon	19.76 ± 0.98	12.01 ± 0.56	39.25%	90-110	3-10

Level of suppression was a percentage decrement of total Mg²⁺ absorption in 24-wk omeprazole-treated rats compared with the corresponding control rats.

Citation: Suksridechacin N, Kulwong P, Chamniansawat S, Thongon N. Effect of prolonged omeprazole administration on segmental intestinal Mg²⁺ absorption in male Sprague-Dawley rats. World J Gastroenterol 2020; 26(11): 1142-1155
URL: https://www.wjgnet.com/1007-9327/full/v26/i11/1142.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i11.1142