Jia ZF, Cao DH, Wu YH, Jin MS, Pan YC, Cao XY, Jiang J. Lethal-7-related polymorphisms are associated with susceptibility to and prognosis of gastric cancer. World J Gastroenterol 2019; 25(8): 1012-1023 [PMID: 30833806 DOI: 10.3748/wjg.v25.i8.1012]
Corresponding Author of This Article
Jing Jiang, PhD, Professor, Statistician, Division of Clinical Research, the First Hospital of Jilin University, No. 71, Xinmin Street, Changchun 130021, Jilin Province, China. jiangjing19702000@jlu.edu.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Table 6 Multivariate Cox regression analysis of gastric cancer survival
Variable
Comparison
HR
95%CI
P value
rs10889677
each increase in C allele
1.25
1.05-1.49
0.012
Age (yr)
> 65 vs ≤ 65
1.39
1.10-1.75
0.005
TNM stage
II vs I
3.49
1.88-6.48
< 0.001
III vs I
11.12
6.00-20.61
< 0.001
Lymphovascular invasion
Positive vs Negative
1.89
1.32-2.72
0.001
Chemotherapy
Yes vs No
0.74
0.59-0.95
0.016
Citation: Jia ZF, Cao DH, Wu YH, Jin MS, Pan YC, Cao XY, Jiang J. Lethal-7-related polymorphisms are associated with susceptibility to and prognosis of gastric cancer. World J Gastroenterol 2019; 25(8): 1012-1023