Genomic variability of Helicobacter pylori isolates of gastric regions from two Colombian populations

Table 1 Prevalence of cagA and vacA alleles of Helicobacter pylori according to site of the stomach

Alleles	Tumaco n = 41			P value	Túquerres n = 31			P value
	Antrum		Body		Antrum		Body
	Lesser curvature	Greater curvature	Greater curvature		Lesser curvature	Greater curvature	Greater curvature
cagA
cagA (+)	85.4%	100%	100%	0.002	96.4%	100%	100%	0.36
cagA (-)	14.6%	0%	0%		0%	0%	0%
vacA
m1	73.2%	78.1%	70.7%	0.360	71.0%	61.3%	58.1%	0.26
m2	26.8%	21.9%	24.3%		12.9%	22.6%	35.5%
vacA
s1	80.5%	78.5%	80.5%	0.730	74.2%	80.7%	64.5%	0.44
s2	19.5%	19.5%	19.5%		19.4%	19.4%	25.8%

Table 2 Type of colonization of Helicobacter pylori according to gender, age and cancer risk

Features	Type of colonization		Total n = 72	P value
	Single	Multiple
	n = 34	n = 38
Gender				0.067
Male	26.5%	47.4%	37.5%
Female	73.5%	52.6%	62.5%
Age (yr)				0.633
18-35	41.2%	36.8%	38.9%
36-47	26.5%	36.8%	31.9%
48-63	32.4%	26.3%	29.2%
Cancer risk				0.027
Low (Tumaco)	70.6%	44.7%	56.9%
High (Túquerres)	29.4%	55.3%	43.1%
Type of gastritis				0.203
Non atrophic	79.4%	89.5%	84.7%
MAG	20.6%	7.9%	13.9%

Table 3 Risk of multiple colonization of Helicobacter pylori in the stomach

Characteristics	Odds ratio	95%CI		P > z
Gender
Female	1.000
Male	2.477	0.858	7.154	0.094
Age (yr)
18-35	1.000
36-47	1.401	0.412	4.769	0.589
48-63	1.160	0.330	4.076	0.816
Cancer risk
Low (Tumaco)	1.000
High (Túquerres)	2.721	0.973	7.609	0.056
Type of gastritis
Non atrophic	1.000
MAG	0.325	0.066	1.594	0.166