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©The Author(s) 2017.
World J Gastroenterol. Aug 21, 2017; 23(31): 5755-5763
Published online Aug 21, 2017. doi: 10.3748/wjg.v23.i31.5755
Published online Aug 21, 2017. doi: 10.3748/wjg.v23.i31.5755
Table 1 Demographics and lymph node characteristics by location n (%)
Characteristics | Total (n = 168) | Abdominal (n = 78) | Mediastinal (n = 90) | P value |
Size (mm), mean ± SD | 20.3 ± 9.9 | 19.3 ± 9.0 | 21.4 ± 18.4 | 0.280 |
Histology needle | 105 (61.3) | 48 (61.5) | 57 (61.1) | 0.955 |
19-G | 17 (10.1) | 5 (6.4) | 12 (13.3) | |
20-G | 7 (4.2) | 3 (3.9) | 4 (4.4) | |
22-G | 48 (28.6) | 23 (29.5) | 25 (27.8) | |
25-G | 33 (19.6) | 17 (21.8) | 16 (17.8) | |
Cytology needle | 63 (38.7) | 30 (38.5) | 33 (38.9) | 0.955 |
19-G | 4 (2.4) | - | 4 (5.6) | |
22-G | 30 (17.9) | 14 (18.0) | 16 (17.8) | |
25-G | 29 (17.3) | 16 (20.5) | 13 (14.4) | |
No. of passes (median, range) | 214 | 99 (11, 4) | 115 (1, 1-3) |
Table 2 Endoscopic ultrasound fine-needle aspiration/fine-needle biopsy diagnoses and final diagnoses in 168 lymph nodes n (%)
EUS FNA/FNB diagnoses | Final diagnoses | |
Metastasis | ||
Carcinoma | 51 (30.3) | 62 (36.9) |
Neuroendocrine | 2 (1.2) | 2 (1.2) |
Melanoma | 1 (0.6) | 1 (0.6) |
Benign/reactive | ||
Granulomatous | 8 (4.8) | 21 (12.5) |
Unspecific reactive | 100 (59.5) | 66 (39.3) |
Lymphoma | 6 (3.6) | 16 (9.5) |
Table 3 Accuracy of endoscopic ultrasound fine-needle aspiration/fine-needle biopsy for diagnosis of malignancy
Overall (n = 168) | Estimate (%) | 95%CI |
Sensitivity | 74.1% | 63.6-82.4 |
Specificity | 100% | 95.8-100 |
Positive predictive value | 100% | 94.0-100 |
Negative predictive value | 80.6% | 72.1-86.9 |
Accuracy | 87.5% | 81.7-91.7 |
Table 4 Analysis of factors associated with the diagnostic accuracy of endoscopic ultrasound fine-needle aspiration/fine-needle biopsy
Variable | OR (95%CI) | P value | OR (95%CI) | P value |
Mediastinal location | 1.05 (0.42-2.64) | 0.907 | 0.93 (0.30-2.92) | 0.900 |
Histology needle | 1.02 (0.40-2.64) | 0.952 | 1.01 (0.31-3.31) | 0.993 |
No. of passes | 0.58 (0.27-1.24) | 0.161 | 1.54 (0.41-5.80) | 0.522 |
Size | 0.98 (0.93-1.03) | 0.383 | 0.98 (0.93-1.03) | 0.411 |
- Citation: Chin YK, Iglesias-Garcia J, de la Iglesia D, Lariño-Noia J, Abdulkader-Nallib I, Lázare H, Rebolledo Olmedo S, Dominguez-Muñoz JE. Accuracy of endoscopic ultrasound-guided tissue acquisition in the evaluation of lymph nodes enlargement in the absence of on-site pathologist. World J Gastroenterol 2017; 23(31): 5755-5763
- URL: https://www.wjgnet.com/1007-9327/full/v23/i31/5755.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i31.5755