Retrospective Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 21, 2017; 23(31): 5755-5763
Published online Aug 21, 2017. doi: 10.3748/wjg.v23.i31.5755
Accuracy of endoscopic ultrasound-guided tissue acquisition in the evaluation of lymph nodes enlargement in the absence of on-site pathologist
Yung Ka Chin, Julio Iglesias-Garcia, Daniel de la Iglesia, Jose Lariño-Noia, Ihab Abdulkader-Nallib, Hector Lázare, Susana Rebolledo Olmedo, J Enrique Dominguez-Muñoz
Yung Ka Chin, Julio Iglesias-Garcia, Daniel de la Iglesia, Jose Lariño-Noia, Susana Rebolledo Olmedo, J Enrique Dominguez-Muñoz, Department of Gastroenterology and Hepatology, University Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain
Julio Iglesias-Garcia, Daniel de la Iglesia, Jose Lariño-Noia, Susana Rebolledo Olmedo, J Enrique Dominguez-Muñoz, Health Research Institute of Santiago de Compostela (IDIS), University Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain
Ihab Abdulkader-Nallib, Hector Lázare, Department of Pathology, University Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain
Author contributions: Chin YK designed and performed the research and wrote the manuscript; Iglesias-Garcia J designed the research and supervised the report; de la Iglesia D, Lariño-Noia J and Abdulkader-Nallib I contributed to the analysis and supervised the report; Lázare H and Rebolledo Olmedo S assisted with data acquisition; and Dominguez-Muñoz JE supervised the report and overall study supervision.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of University Hospital of Santiago de Compostela, Santiago de Compostela, Spain.
Informed consent statement: The authors of this paper guarantee that all study participants or their legal guardian provided informed written consent regarding personal and medical data collection prior to study enrollment.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: There are no additional data available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Julio Iglesias-Garcia, MD, PhD, Department of Gastroenterology and Hepatology, University Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain. julio.iglesias.garcia@sergas.es
Telephone: +34-98-1951364 Fax: +34-98-1955100
Received: April 9, 2017
Peer-review started: April 10, 2017
First decision: June 1, 2017
Revised: June 15, 2017
Accepted: June 18, 2017
Article in press: June 19, 2017
Published online: August 21, 2017
Processing time: 107 Days and 18.5 Hours
Core Tip

Core tip: This study shows that the accuracy of endoscopic ultrasound-guided tissue acquisition in enlarged lymph nodes is not affected by the type of needle used, the number of needle passes, or the location or characteristics of the enlarged lymph nodes. Histological specimens are essential for establishing the diagnosis of lymphoproliferative disease. Employing complementary imaging techniques, such as contrast enhancement and elastography, might help improve the diagnostic yield.