Apoptosis of human pancreatic carcinoma cell-1 cells induced by Yin Chen Hao Decoction

Table 1 Effects of various concentrations of Yin Chen Hao Decoction on apoptosis of pancreatic carcinoma cell line-1 cells

Concentration (μg/mL)	Treatment time (h)
	24	48	72
Control	0.410 ± 0.007	0.407 ± 0.008	0.406 ± 0.007
5	0.365 ± 0.003a	0.332 ± 0.011b	0.306 ± 0.003b
10	0.327 ± 0.003b	0.311 ± 0.004b	0.247 ± 0.003b
20	0.306 ± 0.004b	0.245 ± 0.003b	0.208 ± 0.002b
40	0.264 ± 0.004b	0.217 ± 0.003b	0.158 ± 0.003b

^aP < 0.05;

^bP < 0.01 vs control group.

Table 2 Apoptotic index of pancreatic carcinoma cell line-1 cells treated with Yin Chen Hao Decoction (%)

	Treatment time (h)
	Control	24	48	72	96
Apoptotic index	1.26 ± 0.31	4.95 ± 0.81	18.63 ± 1.93	35.68 ± 0.37	43.63 ± 1.23
t		-6.12	-13.92	-183.17	-53.90
P value1		P < 0.05	P < 0.05	P < 0.05	P < 0.05

¹vs control group.

Table 3 Positive rate of Bcl-2 expression in pancreatic carcinoma cell line-1 cells treated with Yin Chen Hao Decoction (%)

	Treatment time (h)
	Control	24	48	72	96
Positive rate	36.62 ± 0.69	21.71 ± 0.07	10.60 ± 0.49	7.21 ± 0.45	4.54 ± 0.36
t		31.29	44.51	73.62	59.24
P value1		P < 0.01	P < 0.01	P < 0.01	P < 0.01

¹vs control group.

Table 4 Positive rate of Bax expression in pancreatic carcinoma cell line-1 cells treated with Yin Chen Hao Decoction (%)

	Treatment time (h)
	Control	24	48	72	96
Positive rate	10.29 ± 0.51	20.14 ± 0.79	34.6 ± 0.86	45.24 ± 0.48	58.76 ± 1.47
t		-56.89	-41.68	-69.95	-51.89
P value1		P < 0.001	P < 0.001	P < 0.001	P < 0.001

¹vs control group.