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©2008 The WJG Press and Baishideng.
World J Gastroenterol. Apr 21, 2008; 14(15): 2364-2369
Published online Apr 21, 2008. doi: 10.3748/wjg.14.2364
Published online Apr 21, 2008. doi: 10.3748/wjg.14.2364
Table 1 Demographic and clinical data of the populations studied
Total | Group 1 | Group 2 | Group 3 | Group 4 | |
Number of patients | 1038 | 675 | 211 | 121 | 31 |
Age | 65.9 ± 12.4 | 65.1 ± 12.9 | 67.1 ± 11.9 | 68.1 ± 10.3 | 71.9 ± 9.9 |
Sex | |||||
M/F | 671/367 | 448/227 | 133/78 | 73/48 | 17/14 |
Drugs assumption | |||||
Aspirin or anticoagulant | 22 (2.1%) | 12 (1.77%) | 6 (2.8%) | 4 (3.3%) | |
Associated extra intestinal diseases | |||||
Cardiac diseases | 70 (6.7%) | 47 (6.96%) | 13 (6.16%) | 8 (6.6%) | |
Diabetes Mellitus | 8 (0.7%) | 8 (1.18%) | |||
Chronic Renal Failure | 11 (1.05%) | 4 (0.6%) | 4 (1.89%) | 2 (1.65%) | 1 (3.22%) |
Neoplasms | 32 (3.08%) | 18 (2.6%) | 8 (3.79%) | 5 (4.1%) | 1 (3.22%) |
Liver diseases | 34 (3.3%) | 26 (3.85%) | 5 (2.36%) | 3 (2.47%) | |
Endocrinological diseases | 1 (0.09%) | 1 (0.14%) | |||
Associated intestinal diseases | |||||
Diverticula | 262 (25.2%) | 188 (27.8%) | 51 (24.1%) | 17 (14.04%) | 6 (19.3%) |
CRC | 112 (10.8%) | 60 (8.88%) | 36 (17.06%) | 16 (13.2%) | |
IBD | 31 (2.9%) | 22 (3.25%) | 8 (3.79%) | 1 (0.8%) | |
Ischemic colitis | 8 (0.7%) | 7 (1.03%) | 1 (0.8%) | ||
Melanosis coli | 10 (0.96%) | 8 (1.18%) | 2 (0.94%) | ||
Emorroidi | 39 (3.75%) | 27 (4%) | 9 (4.26%) | 3 (2.47%) | |
Angiodysplasia | 13 (1.25%) | 12 (1.77%) | 1 (0.47%) |
Table 2 Characteristics of polyps resected according to size
Total | Group 1 | Group 2 | Group 3 | Group 4 | |
Number of polypectomy | 1354 | 907 | 287 | 129 | 31 |
Size (mm) | 9.45 ± 9.56 | 4.8 ± 2.18 | 11.8 ± 2.6 | 27.7 ± 5.8 | 46.8 ± 13.02 |
Range | (1-100) | (1-10) | (11-19) | (20-39) | (40-100) |
Shape | |||||
Pedunculated | 388 (28.7%) | 176 (19.4%) | 135 (47%) | 70 (54.3%) | 7 (22.6%) |
Sessile | 966 (71.3%) | 731 (80.6%) | 152 (53%) | 59 (45.7%) | 24 (77.4%) |
Location | |||||
Rectal | 247 (18.3%) | 146 (16.1%) | 54 (18.8%) | 33 (2.6%) | 14(45.4%) |
Sigmoid | 559 (41.3%) | 375 (41.3%) | 119 (41.5%) | 59 (45.7%) | 6 (19.4%) |
Left colon | 184 (13.6%) | 126 (13.9%) | 44 (15.3%) | 13 (10.1%) | 1 (3.2%) |
Splenic flexure | 24 (1.8%) | 14 (1.6%) | 8 (2.8%) | 1 (0.8%) | 1 (3.2%) |
Transverse | 94 (6.9%) | 69 (7.6%) | 17 (5.9%) | 6 (4.7%) | 2 (6.4%) |
Hepatic flexure | 64 (4.7%) | 45 (4.9%) | 12 (4.2%) | 3 (2.3%) | 4 (12.8%) |
Right colon | 129 (9.5%) | 95 (10.5%) | 23 (8%) | 9 (6.9%) | 2 (6.4%) |
Caecum | 53 (3.9%) | 37 (4.1%) | 10 (3.5%) | 5 (3.9%) | 1 (3.2%) |
Histology | |||||
Tubular adenoma | 756 (55.9%) | 596 (65.8%) | 138 (48.1%) | 19 (14.7%) | 3 (9.7%) |
Villous adenoma | 243 (17.9%) | 103 (11.3%) | 48 (16.7%) | 66 (51.2%) | 26 (83.9%) |
Tubulovillous adenoma | 315 (23.3%) | 174 (19.2%) | 97 (33.8%) | 42 (32.6%) | 2 (6.4%) |
Hyperplastic | 40 (2.9%) | 34 (3.7%) | 4 (1.4%) | 2 (1.5%) | |
Dysplasia | |||||
No | 125 (9.2%) | 117 (12.9%) | 6 (2.1%) | 2 (1.5%) | |
LGD | 1078 (79.6%) | 769 (84.8%) | 245 (85.4%) | 57 (44.2%) | 7 (22.6%) |
HGD | 123 (9.1%) | 17 (1.9%) | 32 (11.1%) | 51 (39.5%) | 23 (74.2%) |
Invasive cancer | 28 (2.1%) | 4 (0.4%) | 4 (1.4%) | 19 (14.8%) | 1 (3.2%) |
Technique of polypectomy | |||||
Direct snare | 1294 (95.6%) | 907 (100%) | 255 (88.9%) | 108 (83.7%) | 24 (77.4%) |
Mucosectomy | 56 (4.1%) | 30 (10.4%) | 19 (14.8%) | 7 (22.6%) | |
Endoloop | 4 (0.3%) | 2 (0.7%) | 2 (1.5%) | ||
Complication | |||||
Bleeding | 17 (1.3%) | 4 (0.4%) | 3 (1.05%) | 7 (5.4%) | 3 (9.7%) |
Perforation | 1 (0.07%) | 1 (0.35%) | |||
Technique of hemostasis | |||||
Injection | 13 (76.5%) | 4 (100%) | 2 (66.7%) | 6 (85.7%) | 1 (33.3%) |
Clips | 3 (17.6%) | 1 (33.3%) | 2 (66.7%) | ||
APC | 1 (5.9%) | 1 (14.3%) |
Table 3 Results of the Pearson χ2 test applied in the sub-groups for evaluation of the association between bleeding and variables
P-value | ||||
Group 1 | Group 2 | Group 3 | Group 4 | |
Associated extra intestinal diseases | ||||
Liver diseases | 0.003 | 0.060 | 0.001 | 0.851 |
Location | ||||
Transverse colon | 0.0001 | 0.966 | 0.853 | 0.123 |
Histology | ||||
Hyperplastic polyp | 0.238 | 0.023 | 0.912 | 0.125 |
Dysplasia | ||||
Invasive cancer | 0.996 | 0.0001 | 0.681 | 0.561 |
Associated intestinal diseases | ||||
Colon rectal cancer | 0.130 | 0.384 | 0.922 | 0.036 |
Table 4 Results of NPC test of the four groups examined in relationship with bleeding
P-value | |
Group 1 vs Group 2 | 0.368 |
Group 1 vs Group 3 | 0.0001 |
Group 1 vs Group 4 | 0.001 |
Group 2 vs Group 3 | 0.012 |
Group 2 vs Group 4 | 0.013 |
Group 3 vs Group 4 | 0.407 |
Table 5 Results of the Binary Logistic regression
Coef | SE Coef | Z | P | |
Associated extra intestinal diseases | 0.635 | 0.11 | 5.77 | 0 |
Histology | 0.509 | 0.226 | 2.26 | 0.024 |
Size | 0.0567 | 0.019 | 2.97 | 0.003 |
Table 6 Recent reports of series on large polyp endoscopic resection and our series
Authors | Total (n) | Pedunculated (n) | Sessile (n) | Hemorrhage (%) | Perforation (%) | Other (%) |
Brooker JC et al[3] | 34 | - | 34 | 17.6 | 0 | 5.9 |
Hsieh YH et al[4] | 13 | - | 13 | 0 | 0 | 0 |
Brooker JC et al[5] | 100 | - | 100 | 3 | 0 | 1 |
Walsh RM et al[6] | 117 | - | 117 | 8.5 | 0.8 | 0.8 |
Iishi H et al[7] | 56 | - | 56 | 7 | 0 | 0 |
Zlatanic J et al[8] | 77 | - | 77 | 6.5 | 1.3 | 0 |
Kanamori T et al[9] | 33 | - | 33 | 9.1 | 0 | 0 |
Boix J et al[10] | 74 | - | 74 | 13.5 | 0 | 0 |
Bedogni G et al[11] | 66 | 20 | 42 | 3.1 | 0 | 1.5 |
Binmoeller K et al[12] | 176 | 47 | 129 | 24 | 0 | 0 |
Webb WA et al[13] | 102 | 72 | 30 | 7.8 | 0 | 0 |
Nivatvongs S et al[14] | 280 | 196 | 84 | 0.7 | 0 | 1.8 |
Perenz RF et al[15] | 147 | 73 | 74 | 5.4 | 1.3 | 0 |
Dell’Abate P et al[16] | 104 | 49 | 55 | 3.8 | 0 | 0 |
Jameel JK et al[17] | 30 | 6 | 24 | 6.1 | 0 | 0 |
Doniec JM et al[18] | 186 | 45 | 141 | 15 | 0.5 | 0 |
Stergiou N et al[19] | 68 | 27 | 41 | 22.1 | 0 | 0 |
Consolo P et al | 160 | 77 | 83 | 6.2 | 0 | 0 |
- Citation: Consolo P, Luigiano C, Strangio G, Scaffidi MG, Giacobbe G, Giuseppe GD, Zirilli A, Familiari L. Efficacy, risk factors and complications of endoscopic polypectomy: Ten year experience at a single center. World J Gastroenterol 2008; 14(15): 2364-2369
- URL: https://www.wjgnet.com/1007-9327/full/v14/i15/2364.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.2364