Linked color imaging vs Lugol chromoendoscopy for esophageal squamous cell cancer and precancerous lesion screening: A noninferiority study

Figure 1 Flow chart of study design. ESCC: Esophageal squamous cell carcinoma; GI: Gastrointestinal; LCE: Lugol chromoendoscopy; LCI: Linked color imaging; WLI: White light imaging.

Figure 2 A single esophageal squamous cell carcinoma lesion visualized under the three detection methods. A: Under white light imaging; B: Under linked color imaging; C: Under Lugol chromoendoscopy.

Figure 3 Method to measure the color difference between neoplastic and non-neoplastic lesions detected by white light imaging and linked color imaging. A: Neoplastic lesion (1) and non-neoplastic lesion (2) detected by white light imaging; B: Neoplastic lesion (3) and non-neoplastic lesion (4) detected by linked color imaging.