Accuracy of endoscopic ultrasound-guided tissue acquisition in the evaluation of lymph nodes enlargement in the absence of on-site pathologist

Figure 1 Endoscopic ultrasound-guided fine-needle biopsy of an intra-abdominal lymph node. The needle and needle tip are clearly visible inside the targeted lymph node.

Figure 2 Example of a core sample obtained with endoscopic ultrasound-guided tissue acquisition using a biopsy needle.

Figure 3 Small cell carcinoma from an fine-needle aspiration subcarinal lymph node (cell block). A: Note the small cell neoplastic population with hyperchromatic nuclei, scant cytoplasm and absent nucleoli; B: Nuclear positivity for TTF-1; C: Cytoplasmic positivity for synaptophysin.

Figure 4 Flow chart of the selection of endoscopic ultrasound-guided tissue acquisition cases. ¹Fine-needle aspiration/biopsy; ²Rapid on-site evaluation. EUS: endoscopic ultrasound; FNA: Fine-needle aspiration; FNB: Fine-needle biopsy.