Palliative care and end-stage colorectal cancer management: The surgeon meets the oncologist

doi:10.3748/wjg.v20.i24.7602

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Jun 28, 2014 (publication date) through Nov 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 28, 2014; 20(24): 7602-7621
Published online Jun 28, 2014. doi: 10.3748/wjg.v20.i24.7602

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Figure 1 Algorithm for the management of incurable asymptomatic (or minimally symptomatic) stage IV colorectal cancer patients. ¹Depending on the regimen previously administered. KRAS-WT: KRAS-wild type; KRAS-MT: KRAS-mutation; FOLFOX: 5-Fluorouracil + Oxaliplatin; FOLFIRI: 5-Fluorouracil + Irinotecan; NRAS-WT = NRAS-wild type; CRC: Colorectal cancer; CHT: Chemotherapy.

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Figure 2 Algorithm for the management of severely symptomatic incurable stage IV colorectal cancer patients (including emergency cases).

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Figure 3 Improvement of survival after various chemotherapic regimens for incurable stade IV colorectal cancer patients through the last three decades. BSC: Best supportive care; 5-FU: 5-Fluorouracil; FOLFIRI: 5-Fluorouracil + Irinotecan; FOLFOX: 5-Fluorouracil + Oxaliplatin; IFL: 5-Fluorouracil bolus; CAPEOX: Capecitabine + Oxaliplatin; FA: Folic acid (Leucovorin); OS: Overall survival.

Citation: Costi R, Leonardi F, Zanoni D, Violi V, Roncoroni L. Palliative care and end-stage colorectal cancer management: The surgeon meets the oncologist. World J Gastroenterol 2014; 20(24): 7602-7621
URL: https://www.wjgnet.com/1007-9327/full/v20/i24/7602.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i24.7602