Interplay of autophagy and innate immunity in Crohn's disease: A key immunobiologic feature

Figure 1 The autophagic process and types of autophagy.

Figure 2 Schematic illustration of the crosstalk between autophagy and innate immunity in Crohn’s disease. PAMP: Pathogen-associated molecular patterns; DAMP: Damage-associated molecular pattern; ER: Endoplasmic reticulum; UPR: Unfolded protein response; NOD: Nucleotide-binding oligomerization domain-containing protein; MDP: N-acetyl-muramyl-peptide; LPS: Lipopolysaccharide; TLR: Toll-like receptor; XBP1: X-box binding protein 1; IRGM: Immunity-related GTPase family M protein.