Retrospective Cohort Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 7, 2025; 31(13): 104046
Published online Apr 7, 2025. doi: 10.3748/wjg.v31.i13.104046
Nonalcoholic fatty liver disease following laparoscopic duodenum-preserving pancreatic total head resection vs laparoscopic pancreaticoduodenectomy: A retrospective cohort study
Ting-Ting Zhen, Shi-Zhen Li, Shu-Tao Pan, Tao-Yuan Yin, Min Wang, Xing-Jun Guo, Hang Zhang, Ren-Yi Qin
Ting-Ting Zhen, Shi-Zhen Li, Shu-Tao Pan, Tao-Yuan Yin, Min Wang, Xing-Jun Guo, Hang Zhang, Ren-Yi Qin, Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China
Co-corresponding authors: Hang Zhang and Ren-Yi Qin.
Author contributions: Zhen TT, Li SZ collected data, performed statistical analysis, and wrong the original draft; Pan ST, Yin TY, Wang M reviewed and edited the manuscript; Guo XJ, Zhang H, Qin RY designed the research study, funding acquisition, technical or material support. The decision to designate Dr. Qin and Dr. Zhang as co-corresponding authors is well-justified, as both made indispensable and complementary contributions to the research and its successful publication. Dr. Qin’s leadership in designing the research methodology, particularly in integrating surgical approaches with non-alcoholic fatty liver disease research, was foundational to the study’s innovative direction. Furthermore, Dr. Qin’s efforts in securing essential funding were critical to initiating and sustaining the project, ensuring its feasibility and continuity. On the other hand, Dr. Zhang’s meticulous review of the first draft and his provision of detailed, constructive feedback were pivotal in refining the manuscript. His insights ensured that the paper adhered to rigorous disciplinary standards and met the stringent requirements for publication. Together, their combined expertise and efforts advanced the research and enhanced its quality and impact.
Supported by National Natural Science Foundation of China, No. 82273442.
Institutional review board statement: This retrospective cohort study was reviewed and approved by the Ethics Committee of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. TJ-IRB202401014.
Informed consent statement: The requirement for patient consent was waived owing to the retrospective nature of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: The data supporting this study's findings are available from the author, Ting-Ting Zhen, upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ren-Yi Qin, PhD, Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan 430030, Hubei Province, China. ryqin@tjh.tjmu.edu.cn
Received: December 11, 2024
Revised: February 21, 2025
Accepted: March 10, 2025
Published online: April 7, 2025
Processing time: 114 Days and 2.2 Hours
Core Tip

Core Tip: Our study demonstrates that laparoscopic pancreatic total head resection with preservation of the duodenum is more effective than laparoscopic pancreatic head duodenectomy in preventing postoperative nonalcoholic fatty liver disease. In addition, we identified the factors associated with the development of fatty liver after pancreatic surgery.