Enhancing prognostic accuracy in predicting rectal neuroendocrine neoplasms

doi:10.3748/wjg.v30.i37.4087

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Oct 7, 2024 (publication date) through Sep 27, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 7, 2024; 30(37): 4087-4089
Published online Oct 7, 2024. doi: 10.3748/wjg.v30.i37.4087

Enhancing prognostic accuracy in predicting rectal neuroendocrine neoplasms

Renin Peter AA Raj, Abdulqadir J Nashwan

Renin Peter AA Raj, Department of Medicine, Aston Medical School, Birmingham B4 7ET, United Kingdom

Abdulqadir J Nashwan, Department of Nursing & Midwifery Research, Hamad Medical Corporation, Doha 3050, Qatar

Author contributions: Raj RPA, Nashwan AJ contributed to writing the draft and critically reviewing the literature.

Conflict-of-interest statement: All the authors declare that they have no conflicts of interest.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/

Corresponding author: Abdulqadir J Nashwan, MSc, PhD, Research Scientist, Department of Nursing & Midwifery Research, Hamad Medical Corporation, Rayyan Road, Doha 3050, Qatar. anashwan@hamad.qa

Received: August 4, 2024
Revised: August 19, 2024
Accepted: September 5, 2024
Published online: October 7, 2024
Processing time: 53 Days and 2.1 Hours

Core Tip

Core Tip: The GATIS score, developed from a 12-year study of 1408 patients with rectal neuroendocrine neoplasms (R-NENs) across 17 major Chinese centers, predicts overall survival and progression-free survival more accurately than World Health Organization grade and tumor-node-metastasis staging. This score offers improved personalized patient management and treatment planning. However, the study includes limitations such as short follow-up durations and exclusion of molecular and genetic factors. Addressing these in future research could further enhance treatment strategies for R-NENs.