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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 21, 2023; 29(15): 2294-2309
Published online Apr 21, 2023. doi: 10.3748/wjg.v29.i15.2294
Published online Apr 21, 2023. doi: 10.3748/wjg.v29.i15.2294
Ferroptosis inhibition attenuates inflammatory response in mice with acute hypertriglyceridemic pancreatitis
Yi-Teng Meng, Department of Gastroenterology, Shenzhen People’s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong Province, China
Yi Zhou, Pei-Yu Han, Wuxi School of Medicine, Jiangnan University, Wuxi 214000, Jiangsu Province, China
Hong-Bo Ren, Department of Gastroenterology, Qilu Hospital, Jinan 250012, Shandong Province, China
Author contributions: Meng YT, Zhou Y, Han PY, and Ren HB designed the study; Meng YT, Zhou Y and Han PY participated in data collection and wrote the paper; Ren HB and Han PY were responsible for revising the manuscript, contributing the same to the paper; All the listed authors have contributed and approved the final manuscript.
Supported by the National Natural Science Foundation of Shandong Province , No. ZR2021MH032 .
Institutional animal care and use committee statement: This study was approved by the Ethics Committee of Scientific Research of Jinan University Application for Laboratory Animal Ethical Review, No. 20210303-06.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong-Bo Ren, PhD, Professor, Department of Gastroenterology, Qilu Hospital, No. 107 Wenhuaxi Road, Jinan 250012, Shandong Province, China.
Received: December 6, 2022
Peer-review started: December 6, 2022
First decision: January 22, 2023
Revised: February 20, 2023
Accepted: March 21, 2023
Article in press: March 21, 2023
Published online: April 21, 2023
Processing time: 129 Days and 12.7 Hours
Peer-review started: December 6, 2022
First decision: January 22, 2023
Revised: February 20, 2023
Accepted: March 21, 2023
Article in press: March 21, 2023
Published online: April 21, 2023
Processing time: 129 Days and 12.7 Hours
Core Tip
Core Tip: Ferroptosis is involved in the development of inflammatory diseases, but its relationship with acute hypertriglyceridemic pancreatitis (HTGP) remains unclear. This study discoverd ferroptosis is involved in the process of HTGP and therefore a potential target for clinical treatment.