Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 21, 2022; 28(27): 3524-3531
Published online Jul 21, 2022. doi: 10.3748/wjg.v28.i27.3524
Isolated gastric variceal bleeding related to non-cirrhotic portal hypertension following oxaliplatin-based chemotherapy: A case report
Xu Zhang, Yan-Ying Gao, De-Zhao Song, Bao-Xin Qian
Xu Zhang, Yan-Ying Gao, Department of Gastroenterology and Hepatology, The Third Central Hospital of Tianjin; Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases; Artificial Cell Engineering Technology Research Center; Tianjin Institute of Hepatobiliary Disease, Tianjin 300000, China
De-Zhao Song, Department of Interventional Radiology, The Third Central Hospital of Tianjin; Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases; Artificial Cell Engineering Technology Research Center; Tianjin Institute of Hepatobiliary Disease, Tianjin 300000, China
Bao-Xin Qian, Department of Gastroenterology and Hepatology, The Third Central Hospital of Tianjin; Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases; Artificial Cell Engineering Technology Research Center; Tianjin Institute of Hepatobiliary Disease, Tianjin 300000, China
Author contributions: Zhang X and Gao YY contributed equally to this article; Zhang X and Gao YY contributed to writing-original draft preparation; Song DZ contributed to performing transjugular liver biopsy; and Qian BX contributed to writing-reviewing and editing.
Supported by Tianjin Science and Technology Plan Project, No. 19ZXDBSY00030.
Informed consent statement: The legal guardian of the study participant provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bao-Xin Qian, MD, Attending Doctor, Department of Gastroenterology and Hepatology, The Third Central Hospital of Tianjin; Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases; Artificial Cell Engineering Technology Research Center; Tianjin Institute of Hepatobiliary Disease, No. 83 Jintang Road, Hedong District, Tianjin 300000, China. baoxinqian@126.com
Received: December 26, 2021
Peer-review started: December 26, 2021
First decision: April 16, 2022
Revised: April 27, 2022
Accepted: June 26, 2022
Article in press: June 26, 2022
Published online: July 21, 2022
Core Tip

Core Tip: The occurrence of portal hypertension after oxaliplatin chemotherapy is mostly considered to be related to sinusoidal obstruction syndrome, and few studies clearly support non-cirrhotic portal hypertension (NCPH). We present a case of isolated gastric variceal bleeding after oxaliplatin chemotherapy. The pathological results support NCPH.