Purschke B, Bolm L, Meyer MN, Sato H. Interventional strategies in infected necrotizing pancreatitis: Indications, timing, and outcomes. World J Gastroenterol 2022; 28(27): 3383-3397 [PMID: 36158258 DOI: 10.3748/wjg.v28.i27.3383]
Corresponding Author of This Article
Hiroki Sato, MD, PhD, Academic Fellow, Chief Doctor, Research Fellow, Department of Medicine, Asahikawa Medical University, 1-1, Midorigaoka Higashi 2 Jyo 1 Chome, Asahikawa 0788510, Hokkaido, Japan. hirokisato@asahikawa-med.ac.jp
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Jul 21, 2022; 28(27): 3383-3397 Published online Jul 21, 2022. doi: 10.3748/wjg.v28.i27.3383
Interventional strategies in infected necrotizing pancreatitis: Indications, timing, and outcomes
Birte Purschke, Louisa Bolm, Max Nikolaus Meyer, Hiroki Sato
Birte Purschke, Louisa Bolm, Department of Gastrointestinal Surgery, Massachusetts General Hospital, Boston, MA 02114, United States
Max Nikolaus Meyer, Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, United States
Hiroki Sato, Department of Medicine, Asahikawa Medical University, Asahikawa 0788510, Hokkaido, Japan
Hiroki Sato, Department of Gastroenterology, Asahikawa Kosei Hospital, Asahikawa 0788211, Hokkaido, Japan
Author contributions: Purschke B wrote and edited the manuscript, and collected the clinical data and evidence; Bolm L edited the manuscript and reviewed the discussion about interventional surgical strategies; Meyer MN reviewed the manuscript and provided recommendations on treatment strategies; Sato H reviewed the manuscript and provided strategies and recommendations on the endoscopic intervention part; all authors have read and approved the final manuscript.
Supported byJapan Society for the Promotion of Science KAKENHI, No. 19K17480 and No. 21KK0283 (to Sato H).
Conflict-of-interest statement: Authors declare no conflicts of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hiroki Sato, MD, PhD, Academic Fellow, Chief Doctor, Research Fellow, Department of Medicine, Asahikawa Medical University, 1-1, Midorigaoka Higashi 2 Jyo 1 Chome, Asahikawa 0788510, Hokkaido, Japan. hirokisato@asahikawa-med.ac.jp
Received: January 20, 2022 Peer-review started: January 20, 2022 First decision: February 24, 2022 Revised: March 7, 2022 Accepted: June 15, 2022 Article in press: June 15, 2022 Published online: July 21, 2022 Processing time: 179 Days and 5.6 Hours
Core Tip
Core Tip: Acute pancreatitis remains a potentially life-threatening disease. Necrotizing pancreatitis (NP) is associated with superinfection and increases the mortality rate. We summarized the current evidence and clinical recommendations of multidisciplinary approaches focusing on conservative, interventional, and surgical treatment. The interventional approach is often required as a first step in treating infected NP, while further options include minimal invasive or an escalation to open surgical treatment. Although this “step-up approach” is well-established, the exact timing, sequence, and procedure choice remain controversial; this review aims to summarize current evidence and to provide guidance for decision making in clinical practice.
