Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 21, 2021; 27(35): 5958-5966
Published online Sep 21, 2021. doi: 10.3748/wjg.v27.i35.5958
Effectiveness and safety of over-the-scope clip in closing perforations after duodenal surgery
Zhen-Zhen Wang, Xian-Bin Zhou, Yi Wang, Xin-Li Mao, Li-Ping Ye, Ling-Ling Yan, Ya-Hong Chen, Ya-Qi Song, Yue Cai, Shi-Wen Xu, Shao-Wei Li
Zhen-Zhen Wang, Xian-Bin Zhou, Yi Wang, Xin-Li Mao, Li-Ping Ye, Ling-Ling Yan, Ya-Qi Song, Yue Cai, Shao-Wei Li, Key Laboratory of Minimally Invasive Techniques and Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai 317000, Zhejiang Province, China
Zhen-Zhen Wang, Xian-Bin Zhou, Yi Wang, Xin-Li Mao, Li-Ping Ye, Ling-Ling Yan, Ya-Qi Song, Yue Cai, Shao-Wei Li, Department of Gastroenterology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai 317000, Zhejiang Province, China
Ya-Hong Chen, Health Management Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai 317000, Zhejiang Province, China
Shi-Wen Xu, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai 317000, Zhejiang Province, China
Author contributions: Wang ZZ, Zhou XB, Wang Y, Mao XL, and Ye LP participated in the clinical treatment; Xu SW, Yan LL, and Li SW wrote the original draft; Song YQ, Cai Y, and Chen YH undertook validation, writing, review, and editing; all authors contributed to the article and approved the submitted version.
Supported by Program of Taizhou Science and Technology Grant, No. 20ywb29; Medical Health Science and Technology Project of Zhejiang Province, No. 2021PY083 and No. 2019KY239; Key Technology Research and Development Program of Zhejiang Province, No. 2019C03040; Major Research Program of Taizhou Enze Medical Center Grant, No. 19EZZDA2; and Open Fund of Key Laboratory of Key Laboratory of Minimally Invasive Techniques & Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, No. 21SZDSYS01 and No. 21SZDSYS09.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University Institutional Review Board (approval No. K20210412).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that they have no conflict interests.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shao-Wei Li, PhD, Academic Fellow, Assistant Professor, Associate Research Scientist, Instructor, Key Laboratory of Minimally Invasive Techniques and Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, No. 150 Xinmen Street, Linhai 317000, Zhejiang Province, China. li_shaowei81@hotmail.com
Received: May 10, 2021
Peer-review started: May 10, 2021
First decision: June 27, 2021
Revised: July 8, 2021
Accepted: August 18, 2021
Article in press: August 18, 2021
Published online: September 21, 2021
Processing time: 128 Days and 2.3 Hours
Core Tip

Core Tip: This study presents the use of over-the-scope clip in closing duodenal perforation of 18 patients. We believe that our study makes a significant contribution to the literature because dealing with perforation after endoscopic resection of duodenal subepithelial lesions is challenging. This study aimed to evaluate the effectiveness and safety of over-the-scope clip in closing perforation after endoscopic resection of duodenal subepithelial lesions. The rate of successful closure was 100%. No delayed perforation occurred in any of the patients. Seven patients had postoperative infection, of which 1 patient developed septic shock and underwent surgery. All 18 patients recovered.