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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Effectiveness and safety of over-the-scope clip in closing perforations after duodenal surgery
Zhen-Zhen Wang, Xian-Bin Zhou, Yi Wang, Xin-Li Mao, Li-Ping Ye, Ling-Ling Yan, Ya-Hong Chen, Ya-Qi Song, Yue Cai, Shi-Wen Xu, Shao-Wei Li
Zhen-Zhen Wang, Xian-Bin Zhou, Yi Wang, Xin-Li Mao, Li-Ping Ye, Ling-Ling Yan, Ya-Qi Song, Yue Cai, Shao-Wei Li, Key Laboratory of Minimally Invasive Techniques and Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai 317000, Zhejiang Province, China
Zhen-Zhen Wang, Xian-Bin Zhou, Yi Wang, Xin-Li Mao, Li-Ping Ye, Ling-Ling Yan, Ya-Qi Song, Yue Cai, Shao-Wei Li, Department of Gastroenterology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai 317000, Zhejiang Province, China
Ya-Hong Chen, Health Management Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai 317000, Zhejiang Province, China
Shi-Wen Xu, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai 317000, Zhejiang Province, China
Author contributions: Wang ZZ, Zhou XB, Wang Y, Mao XL, and Ye LP participated in the clinical treatment; Xu SW, Yan LL, and Li SW wrote the original draft; Song YQ, Cai Y, and Chen YH undertook validation, writing, review, and editing; all authors contributed to the article and approved the submitted version.
Supported by Program of Taizhou Science and Technology Grant, No. 20ywb29; Medical Health Science and Technology Project of Zhejiang Province, No. 2021PY083 and No. 2019KY239; Key Technology Research and Development Program of Zhejiang Province, No. 2019C03040; Major Research Program of Taizhou Enze Medical Center Grant, No. 19EZZDA2; and Open Fund of Key Laboratory of Key Laboratory of Minimally Invasive Techniques & Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, No. 21SZDSYS01 and No. 21SZDSYS09.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University Institutional Review Board (approval No. K20210412).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that they have no conflict interests.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
http://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Shao-Wei Li, PhD, Academic Fellow, Assistant Professor, Associate Research Scientist, Instructor, Key Laboratory of Minimally Invasive Techniques and Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, No. 150 Xinmen Street, Linhai 317000, Zhejiang Province, China. li_shaowei81@hotmail.com
Received: May 10, 2021
Peer-review started: May 10, 2021
First decision: June 27, 2021
Revised: July 8, 2021
Accepted: August 18, 2021
Article in press: August 18, 2021
Published online: September 21, 2021
ARTICLE HIGHLIGHTS
Research background
Currently, endoscopic resection of duodenal subepithelial lesions (SELs) is a challenging procedure with a high risk of perforation.
Research motivation
It is importance to deal with perforation after endoscopic resection of duodenal SELs. However, so far, there were few reports on endoscopic methods for management of perforations.
Research objectives
We aim to evaluate the effectiveness and safety of over-the-scope clip (OTSC) in the closing the perforation after endoscopic resection of duodenal SELs.
Research methods
This was a retrospective study. We collected data of 18 consecutive patients who were treated with OTSCs to close the perforation after endoscopic resection of duodenal SELs and analyzed the rate of complete resection, closure of intraprocedural perforation, delayed bleeding, delayed perforation, and postoperative infection.
Research results
All the perforations after endoscopic resection of duodenal SELs were successfully closed. No delayed bleeding or perforation occurred in any of the patients.
Research conclusions
OTSC can effectively and safely close the perforations after endoscopic resection of duodenal SELs by an experienced endoscopist.
Research perspectives
We need to expand the sample size to confirm further the effectiveness and safety of OTSC in closing the perforation after endoscopic resection of duodenal SELs. In addition, the long-term outcome of OTSC should be observed by extending the follow-up time.
