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World J Gastroenterol. Jul 7, 2021; 27(25): 3802-3814
Published online Jul 7, 2021. doi: 10.3748/wjg.v27.i25.3802
Emerging applications of radiomics in rectal cancer: State of the art and future perspectives
Min Hou, Ji-Hong Sun
Min Hou, Ji-Hong Sun, Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, Zhejiang Province, China
Author contributions: Hou M wrote and revised the manuscript for important intellectual content; Sun JH made critical revisions related to important intellectual content of the manuscript; both authors approved the final version of the article.
Supported by The National Natural Science Foundation of China, No. 81871403; and the Key Research and Development Program of Zhejiang Province, No. 2019C03014.
Conflict-of-interest statement: The authors declare no conflict of interests related to this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ji-Hong Sun, MD, PhD, Attending Doctor, Professor, Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 3 East Qingchun Road, Hangzhou 310016, Zhejiang Province, China. sunjihong@zju.edu.cn
Received: January 27, 2021
Peer-review started: January 27, 2021
First decision: May 2, 2021
Revised: May 6, 2021
Accepted: May 21, 2021
Article in press: May 21, 2021
Published online: July 7, 2021
Processing time: 159 Days and 13.1 Hours
Core Tip

Core Tip: Radiomics has exhibited significant potential for risk stratification of rectal cancer and has yielded excellent performance in response assessment of neoadjuvant radiochemotherapy. While the past 3 years has witnessed an exponential growth of the field, research on radiomics remains in its infancy and is constantly evolving. More rigorous analyses are emerging, and improvements in bias reduction techniques accompanied with multicentric studies will hopefully enable more robust and generalizable models. Here, we review recent updates on the use of radiomics based on computed tomography and magnetic resonance imaging in the detection and evaluation of rectal cancer.