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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 7, 2021; 27(1): 37-54
Published online Jan 7, 2021. doi: 10.3748/wjg.v27.i1.37
Published online Jan 7, 2021. doi: 10.3748/wjg.v27.i1.37
Lipidome is lipids regulator in gastrointestinal tract and it is a life collar in COVID-19: A review
Khaled Mohamed Mohamed Koriem, Medical Physiology Department, Medical Research Division, National Research Centre, Dokki 12622, Cairo, Egypt
Author contributions: Koriem KMM designed the review study, conceived of the manuscript, conducted the literature search and wrote the first and final versions of the manuscript.
Conflict-of-interest statement: The author declares no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Khaled Mohamed Mohamed Koriem, PhD, Professor, Medical Physiology Department, Medical Research Division, National Research Centre, 33 El-Buhouth Street, Dokki 12622, Cairo, Egypt. kkoriem@yahoo.com
Received: November 16, 2020
Peer-review started: November 16, 2020
First decision: November 25, 2020
Revised: December 2, 2020
Accepted: December 17, 2020
Article in press: December 17, 2020
Published online: January 7, 2021
Peer-review started: November 16, 2020
First decision: November 25, 2020
Revised: December 2, 2020
Accepted: December 17, 2020
Article in press: December 17, 2020
Published online: January 7, 2021
Core Tip
Core Tip: The lipidome is mentioned to the total amount of the lipids inside the biological cells. The lipid enters the human gastrointestinal tract through external source and internal source. The tissue distribution of lipid is completely different among different species. The lipids play an important role in many stages of the viral replication cycle. The specific lipid change occurs during viral infection. The virus connects with blood-borne lipoproteins and apolipoprotein E. The viral interest is cholesterol- and lipid raft-dependent molecules. This review focuses on the important of lipidome in both gastrointestinal fat absorption and coronavirus disease 2019 infection.