Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 28, 2020; 26(36): 5520-5526
Published online Sep 28, 2020. doi: 10.3748/wjg.v26.i36.5520
Published online Sep 28, 2020. doi: 10.3748/wjg.v26.i36.5520
SMARCB1/INI1-deficient pancreatic undifferentiated rhabdoid carcinoma mimicking solid pseudopapillary neoplasm: A case report and review of the literature
Yinan Hua, Piyush Soni, Douglas Larsen, Riyam Zreik, Bing Leng, Debby Rampisela, Department of Pathology, Baylor Scott & White Health, Texas A&M University College of Medicine, Temple, TX 76508, United States
Author contributions: All authors contributed to the writing and revising of the manuscript.
Informed consent statement: Informed written consent was obtained.
Conflict-of-interest statement: No conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Debby Rampisela, MD, Attending Doctor, Department of Pathology, Baylor Scott & White Health, Texas A&M University College of Medicine, 2401 S. 31st Street, MS-01-266, Temple, TX 76508, United States. debby.rampisela@bswhealth.org
Received: June 10, 2020
Peer-review started: June 11, 2020
First decision: June 18, 2020
Revised: June 29, 2020
Accepted: September 5, 2020
Article in press: September 5, 2020
Published online: September 28, 2020
Processing time: 105 Days and 16.5 Hours
Peer-review started: June 11, 2020
First decision: June 18, 2020
Revised: June 29, 2020
Accepted: September 5, 2020
Article in press: September 5, 2020
Published online: September 28, 2020
Processing time: 105 Days and 16.5 Hours
Core Tip
Core Tip: The presence of a pseudopapillary architectural pattern in pancreatic tumors sampled via fine needle aspiration commonly leads to solid pseudopapillary neoplasm as the primary diagnostic consideration, particularly in middle-aged women; however, an inconclusive immunohistochemistry profile may suggest an alternative diagnosis. Our case highlights that while SMARCB1/INI1-deficient pancreatic undifferentiated carcinomas may mimic solid pseudopapillary neoplasm, recognition of this aggressive malignancy is important as these rare tumors impart a dismal prognosis.