Retrospective Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 7, 2020; 26(17): 2082-2096
Published online May 7, 2020. doi: 10.3748/wjg.v26.i17.2082
Prediction of different stages of rectal cancer: Texture analysis based on diffusion-weighted images and apparent diffusion coefficient maps
Jian-Dong Yin, Li-Rong Song, He-Cheng Lu, Xu Zheng
Jian-Dong Yin, Li-Rong Song, Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110003, Liaoning Province, China
He-Cheng Lu, College of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110036, Liaoning Province, China
Xu Zheng, Department of Clinical Oncology, Shengjing Hospital of China Medical University, Shenyang 110011, Liaoning Province, China
Author contributions: Yin JD designed this study; Lu HC performed the research; Song LR wrote the paper; Yin JD supervised the report; Zheng X provided clinical advice.
Supported by Research and Development Foundation for Major Science and Technology from Shenyang, No. 19-112-4-105; Big Data Foundation for Health Care from China Medical University, No. HMB201902105; and Natural Fund Guidance Plan from Liaoning, No. 2019-ZD-0743.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Shengjing Hospital of China Medical University.
Informed consent statement: Written informed consent was acquired from each patient.
Conflict-of-interest statement: All authors declare no conflicts-of-interest related to this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Xu Zheng, MD, Associate Professor, Department of Clinical Oncology, Shengjing Hospital of China Medical University, No. 39, Huaxiang Street, Tiexi District, Shenyang 110011, Liaoning Province, China. cmuzhengxu@126.com
Received: February 6, 2020
Peer-review started: February 6, 2020
First decision: February 29, 2020
Revised: March 26, 2020
Accepted: April 15, 2020
Article in press: April 15, 2020
Published online: May 7, 2020
Core Tip

Core tip: This retrospective study investigated the correlations between stages of rectal cancer and texture features from diffusion-weighted images and apparent diffusion coefficient maps. The area under the operating characteristic curve reached 0.793 for identifying local invasion (T stage), and reached 0.802 for determining nodal involvement (N stage). Texture analysis based on diffusion-weighted images and apparent diffusion coefficient maps showed potential value in classifying N and T stage rectal cancer.