Young CJ, Zahid A, Koh CE, Young JM. Hypothesized summative anal physiology score correlates but poorly predicts incontinence severity. World J Gastroenterol 2017; 23(31): 5732-5738 [PMID: 28883698 DOI: 10.3748/wjg.v23.i31.5732]
Corresponding Author of This Article
Dr. Christopher J Young, Professor, RPAH Medical Centre, Suite 415, 100 Carillon Avenue, Sydney, NSW 2042, Australia. cyoungnsw@aol.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Cohort Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Christopher J Young, Assad Zahid, Cherry E Koh, Jane M Young
Christopher J Young, Assad Zahid, Cherry E Koh, Department of Colorectal Surgery, University of Sydney, Sydney, NSW 2042, Australia
Christopher J Young, RPAH Medical Centre, Sydney, NSW 2042, Australia
Christopher J Young, Assad Zahid, Discipline of Surgery, University of Sydney, Sydney, NSW 2042, Australia
Cherry E Koh, Jane M Young, Surgical Outcome Research Centre (SOuRCe), Royal Prince Alfred Hospital, University of Sydney, Sydney, NSW 2042, Australia
Jane M Young, School of Public health, University of Sydney, Sydney, NSW 2006, Australia
Author contributions: Young CJ, Koh CE and Young JM designed the research; Young CJ, Zahid A, Koh CE and Young JM performed the research; Young CJ and Zahid A contributed new ideas to the manuscript publications; Koh CE and Young JM analyzed the data; Young CJ, Zahid A, Koh CE and Young JM wrote the paper.
Institutional review board statement: This study proves by University of Sydney Institutional Review Board.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: None of them has received fees for serving as a speaker, or been a consultant and/or an advisory board member for any organization(s). None has received research funding for this project. None owns stocks and/or shares relevant to this research. None owns any patents
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Christopher J Young, Professor, RPAH Medical Centre, Suite 415, 100 Carillon Avenue, Sydney, NSW 2042, Australia. cyoungnsw@aol.com
Telephone: +61-2-95197576 Fax: +61-2-95191806
Received: March 13, 2017 Peer-review started: March 14, 2017 First decision: May 16, 2017 Revised: June 14, 2017 Accepted: July 12, 2017 Article in press: July 12, 2017 Published online: August 21, 2017 Processing time: 158 Days and 22.9 Hours
Core Tip
Core tip: This study explored the relationship between a hypothesized anal physiology score combining rankings from maximal manometric resting pressures and anal canal length, ultrasound proportions of anal canal length of internal and external anal sphincters which were intact, and bilateral pudendal nerve terminal motor latencies; with the Cleveland Clinic Continence Score. The association between physiology and continence scores was significant but accounted for only 9.2% of the variability. The most useful variables predicting continence score were proportion of external sphincter intact, pudendal neuropathy and previous pelvic surgery. This study shows anal physiology tests predict continence scores better when considered collectively.
