Case Report
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 21, 2016; 22(27): 6328-6334
Published online Jul 21, 2016. doi: 10.3748/wjg.v22.i27.6328
Bile cast nephropathy: A case report and review of the literature
Jaymon Patel, Saqib Walayat, Nikhil Kalva, Sidney Palmer-Hill, Sonu Dhillon
Jaymon Patel, Sidney Palmer-Hill, Department of Internal Medicine, University of Illinois Peoria Campus, OSF Saint Francis Medical Center, Peoria, IL 61637, United States
Saqib Walayat, Nikhil Kalva, Sonu Dhillon, Department of Gastroenterology and Hepatology, University of Illinois Peoria, Campus, OSF Saint Francis Medical Center, Peoria, IL 61637, United States
Author contributions: Patel J, Walayat S and Kalva N reviewed the literature, drafted the manuscript and approved the final version of the article to be published; Dhillon S reviewed the literature, made critical revisions related to the content of the article and approved the final version of the article to be published; Palmer-Hill S edited the article to be published.
Institutional review board statement: This case report was exempt from the Institutional Review Board standards at the University Of Illinois College Of Medicine in Peoria.
Informed consent statement: The patient involved in this study gave his written consent authorizing use and disclosure of his protected health information.
Conflict-of-interest statement: All the authors have no conflicts of interests to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jaymon Patel, MD, Department of Internal Medicine, University of Illinois Peoria Campus, OSF Saint Francis Medical Center, 530 NE Glen Oak Ave, Peoria, IL 61637, United States. Jaymon.b.patel@osfhealthcare.org
Telephone: +1-650-7877489
Received: December 30, 2015
Peer-review started: December 31, 2015
First decision: January 28, 2016
Revised: February 29, 2016
Accepted: March 18, 2016
Article in press: March 18, 2016
Published online: July 21, 2016
Core Tip

Core tip: The role of bilirubin in causing acute renal insufficiency is not well known. Our case report is one of few documenting evidence of renal insufficiency as a result of hyperbilirubinemia. Diagnosis requires a high index of suspicion in patients with hyperbilirubinemia with concomitant acute renal insufficiency. Renal biopsy is the solitary means of definitive diagnosis. Treatment is targeted at improving hepatic dysfunction and decreasing bilirubin burden. Numerous treatment modalities to reduce bilirubin have been suggested with variable outcomes.