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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 21, 2016; 22(11): 3296-3301
Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3296
Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3296
Primary advanced esophago-gastric melanoma: A rare case
Lin Wang, Peking University China-Japan Friendship School of Clinical Medicine, Beijing 100029, China
Liang Zong, Department of Gastrointestinal Surgery, Graduate School of Medicine, University of Tokyo, Tokyo 113-8655, Japan
Hidetsugu Nakazato, Department of Surgery, Okinawa Red Cross Hospital, Okinawa 902-8588, Japan
Wen-Yue Wang, Chao-Feng Li, Guo-Chao Zhang, Tao Tang, Department of Gastrointestinal Surgery, China-Japan Friendship Hospital, Beijing 100029, China
Yan-Fen Shi, Department of Pathology, China-Japan Friendship Hospital, Beijing 100029, China
Author contributions: Wang WY and Zong L designed the study; Wang L, Li CF, Shi YF, Zhang GC and Tang T did the experiment and collected the data; Wang L, Wang WY and Zong L wrote the manuscript; Zong L and Nakazato H revised the manuscript; Wang L and Zong L contributed equally to this study.
Institutional review board statement: The study was reviewed and approved by the China-Japan Friendship Hospital Institutional Review Board.
Informed consent statement: Informed written consent was obtained prior to study enrollment.
Conflict-of-interest statement: All authors declared that there is no conflict of interest related to this study.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Wen-Yue Wang, Department of Gastrointestinal Surgery, China-Japan Friendship Hospital, No. 2 Yinghua East Street, Chaoyang District, Beijing 100029, China. wwenyue080@163.com
Telephone: +86-10-84205442 Fax: +86-10-64203096
Received: November 3, 2015
Peer-review started: November 4, 2015
First decision: November 27, 2015
Revised: December 28, 2015
Accepted: January 9, 2016
Article in press: January 11, 2016
Published online: March 21, 2016
Processing time: 131 Days and 17.9 Hours
Peer-review started: November 4, 2015
First decision: November 27, 2015
Revised: December 28, 2015
Accepted: January 9, 2016
Article in press: January 11, 2016
Published online: March 21, 2016
Processing time: 131 Days and 17.9 Hours
Core Tip
Core tip: Primary malignant digestive melanoma is a very rare disease with poor prognosis. Here we report an extremely rare and advanced case of primary esophago-gastric melanoma. Although the effect of combination strategy of surgical resection with chemotherapy or radiotherapy is still unclear, we strongly recommend a postoperative chemotherapy or radiotherapy due to the fast progression and extremely short survival of our case.