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Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 21, 2016; 22(11): 3127-3149
Published online Mar 21, 2016. doi: 10.3748/wjg.v22.i11.3127
Evidence-based medical oncology and interventional radiology paradigms for liver-dominant colorectal cancer metastases
Alan Alper Sag, Fatih Selcukbiricik, Nil Molinas Mandel
Alan Alper Sag, Division of Interventional Radiology, Department of Radiology, Koc University School of Medicine, Istanbul 34450, Turkey
Fatih Selcukbiricik, Nil Molinas Mandel, Division of Medical Oncology, Department of Internal Medicine, Koc University School of Medicine, Istanbul 34450, Turkey
Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: Authors declare no conflicts of interest or potential conflicts of interest for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Alan Alper Sag, MD, Division of Interventional Radiology, Department of Radiology, Koc University School of Medicine, Rumelifeneri Yolu, Sariyer, Istanbul 34450, Turkey. asag@ku.edu.tr
Telephone: +90-212-3381176 Fax: +90-212-3381165
Received: October 27, 2015
Peer-review started: October 27, 2015
First decision: December 11, 2015
Revised: December 22, 2015
Accepted: January 17, 2016
Article in press: January 17, 2016
Published online: March 21, 2016
Processing time: 138 Days and 21.4 Hours
Core Tip

Core tip: Survival is increasing in patients with colorectal cancer because of major advances in the domain of modern chemotherapy and personalized biological agents. As a result, there is increased demand for minimally-invasive non-surgical strategies to treat liver metastases and their recurrences. Non-surgical Interventional Radiology treatments such as percutaneous ablation and endovascular-directed therapy have emerged as adjuncts or alternatives to other forms of treatment in this population.