Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 21, 2015; 21(7): 2206-2209
Published online Feb 21, 2015. doi: 10.3748/wjg.v21.i7.2206
Published online Feb 21, 2015. doi: 10.3748/wjg.v21.i7.2206
Lymphangitic spread from the appendiceal adenocarcinoma to the ileocecal valve, mimicking Crohn’s disease
Tricia Murdock, Maryam Zenali, Department of Pathology, University of Vermont-College of Medicine/Fletcher Allen Health Care, Burlington, VT 05401, United States
Nicholas Lim, Department of Medicine-Gastroenterology, University of Vermont-College of Medicine/Fletcher Allen Health Care, Burlington, VT 05401, United States
Author contributions: Murdock T and Zenali M contributed to concept and design, analysis and interpretation of data, drafting and revising paper critically for important intellectual content; Lim N contributed to analysis and interpretation of data, revising article for important intellectual content; Zenali M contributed to final approval of the version to be published.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Tricia Murdock, MD, Department of Pathology, University of Vermont-College of Medicine/Fletcher Allen Health Care, 111 Colchester Avenue, Burlington, VT 05401, United States. tricia.murdock@vtmednet.org
Telephone: +1-802-8470000 Fax: +1-802-847415
Received: March 27, 2014
Peer-review started: March 27, 2014
First decision: April 15, 2014
Revised: May 31, 2014
Accepted: September 12, 2014
Article in press: September 16, 2014
Published online: February 21, 2015
Processing time: 321 Days and 10.9 Hours
Peer-review started: March 27, 2014
First decision: April 15, 2014
Revised: May 31, 2014
Accepted: September 12, 2014
Article in press: September 16, 2014
Published online: February 21, 2015
Processing time: 321 Days and 10.9 Hours
Core Tip
Core tip: Appendiceal signet ring carcinoma (ASRC) is rare and can be confused with other pathologic processes. This aggressive tumor progresses rapidly with frequent extra-appendiceal spread at the time of diagnosis. It’s clinical and radiologic manifestations are non-discrete and can present as ascities, an ovarian mass or appendicitis. The basis of the paper is to address the peculiar and evasive nature of this tumor. Herein we report a case of ASRC, presenting as confined lymphangitic spread within the illeocecal region, clinically mimicking Crohn’s disease.