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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 21, 2015; 21(39): 11003-11015
Published online Oct 21, 2015. doi: 10.3748/wjg.v21.i39.11003
Published online Oct 21, 2015. doi: 10.3748/wjg.v21.i39.11003
Current status and perspectives in split liver transplantation
Andrea Lauterio, Stefano Di Sandro, Giacomo Concone, Riccardo De Carlis, Alessandro Giacomoni, Luciano De Carlis, Transplant Center, Department of General Surgery and Abdominal Transplantation, Niguarda Cà Granda Hospital, Piazza Ospedale Maggiore 3, 20162 Milan, Italy
Stefano Di Sandro, Giacomo Concone, Riccardo De Carlis, Department of General Surgery, University of Pavia Medical School, 27100 Pavia, Italy
Author contributions: Lauterio A drafted the article critically for important intellectual content; Di Sandro S, Concone G, De Carlis R and Giacomoni A gave substantial contributions to concept and design of the article, acquisition of data, and interpretation of data; Lauterio A and De Carlis L gave the final approval of the version to be published.
Conflict-of-interest statement: The authors listed have NO financial interest, or non-financial interest in the subject matter or materials discussed in this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Andrea Lauterio, MD, FEBS, Transplant Center, Department of General Surgery and Abdominal Transplantation, Niguarda Cà Granda Hospital, Piazza Ospedale Maggiore 3, 20162 Milan, Italy. andrea.lauterio@ospedaleniguarda.it
Telephone: +39-02-64442252 Fax: +39-2-64442893
Received: April 28, 2015
Peer-review started: May 6, 2015
First decision: June 2, 2015
Revised: June 27, 2015
Accepted: August 30, 2015
Article in press: August 30, 2015
Published online: October 21, 2015
Processing time: 174 Days and 2.5 Hours
Peer-review started: May 6, 2015
First decision: June 2, 2015
Revised: June 27, 2015
Accepted: August 30, 2015
Article in press: August 30, 2015
Published online: October 21, 2015
Processing time: 174 Days and 2.5 Hours
Core Tip
Core tip: The transplantation community has made numerous efforts to expand the donor pool. While conventional split liver transplantation in which a child received the left lateral segment and an adult the right liver has proved an effective approach to increase organ availability, current outcomes after split liver transplantation for two adult recipients are conflicting. Ongoing surgical refinements and innovations have been reported and dedicated organ allocation policies proposed to encourage the more widespread application of this challenging procedure in the future.