Case Report
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 7, 2015; 21(21): 6759-6763
Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6759
Reactive lymphoid hyperplasia of the liver: Perinodular enhancement on contrast-enhanced computed tomography and magnetic resonance imaging
Tetsuo Sonomura, Shinpei Anami, Taizo Takeuchi, Motoki Nakai, Shinya Sahara, Hirohiko Tanihata, Kazuki Sakamoto, Morio Sato
Tetsuo Sonomura, Shinpei Anami, Taizo Takeuchi, Motoki Nakai, Morio Sato, Department of Radiology, Wakayama Medical University, Wakayama 641-8510, Japan
Shinya Sahara, Hirohiko Tanihata, Department of Radiology, Kishiwada Tokushukai Hospital, Kishiwada-shi 596-8522, Japan
Kazuki Sakamoto, Department of Surgery, Kishiwada Tokushukai Hospital, Kishiwada-shi 596-8522, Japan
Author contributions: Sahara S and Tanihata H performed diagnostic imaging; Sakamoto K performed partial hepatectomy; Sonomura T, Anami S, Takeuchi T and Nakai M acquired the data and researched the literature; Sonomura T and Sato M drafted and edited the manuscript.
Ethics approval: The patient had a standard treatment that was approved ethically.
Informed consent: Informed consent was obtained in a routine manner.
Conflict-of-interest: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Tetsuo Sonomura, MD, PhD, Department of Radiology, Wakayama Medical University, 811-1 Kimiidera, Wakayama 641-8510, Japan. sonomura@wakayama-med.ac.jp
Telephone: +81-73-441-0605 Fax: +81-73-444-3110
Received: November 5, 2014
Peer-review started: November 9, 2014
First decision: November 26, 2014
Revised: December 10, 2014
Accepted: February 5, 2015
Article in press: February 5, 2015
Published online: June 7, 2015
Processing time: 217 Days and 21.6 Hours
Core Tip

Core tip: It is difficult to differentiate between reactive lymphoid hyperplasia (RLH) of the liver and malignant liver tumors such as hepatocellular carcinoma and liver metastases. We observed a liver nodule with perinodular enhancement in the arterial dominant phase on contrast-enhanced computed tomography and magnetic resonance imaging. We consider that this imaging feature could be a useful clue for identifying RLH in the liver. Histological analysis revealed the liver nodule in our patient to be RLH, with prominent sinusoidal dilatation around the nodule. This dilatation is the cause of the perinodular enhancement, which is useful for the accurate diagnosis of RLH.