Meta-Analysis
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 14, 2015; 21(18): 5707-5718
Published online May 14, 2015. doi: 10.3748/wjg.v21.i18.5707
Association of IL-17 polymorphisms with gastric cancer risk in Asian populations
Zi-Wen Long, Hong-Mei Yu, Ya-Nong Wang, Dan Liu, Yan-Zhi Chen, Yu-Xia Zhao, Lu Bai
Zi-Wen Long, Hong-Mei Yu, Ya-Nong Wang, Dan Liu, Yan-Zhi Chen, Yu-Xia Zhao, Department of Gastric Cancer and Soft-Tissue Sacomas Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China
Zi-Wen Long, Hong-Mei Yu, Ya-Nong Wang, Lu Bai, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
Author contributions: Long ZW and Yu HM contributed equally to this work; Long ZW, Yu HM, Wang YN, Liu D, Chen YZ, Zhao YX and Bai L designed research; Long ZW, Yu HM and Wang YN performed research; Long ZW and Yu HM contributed new reagents/analytic tools; Long ZW and Yu HM analyzed data; and Long ZW and Yu HM wrote the paper.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ya-Nong Wang, MD, Department of Oncology, Shanghai Medical College, Fudan University, Building 3, Room 1208, 270 Dongan Road, Shanghai 200032, China. wangyanong731@163.com
Telephone: +86-21-64175590 Fax: +86-21-64175590
Received: August 8, 2014
Peer-review started: August 9, 2014
First decision: September 27, 2014
Revised: November 5, 2014
Accepted: December 1, 2014
Article in press: December 1, 2014
Published online: May 14, 2015
Processing time: 283 Days and 1.1 Hours
Core Tip

Core tip: There may be a relationship between the IL-17 gene and gastric cancer risk, especially in individuals carrying the rs2275913 G>A and rs763780 T>C polymorphisms. The IL-17 gene polymorphisms might be important in determining an individual’s susceptibility to gastric cancer.