Prospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 14, 2015; 21(18): 5663-5667
Published online May 14, 2015. doi: 10.3748/wjg.v21.i18.5663
Association of Streptococcus bovis presence in colonic content with advanced colonic lesion
Maya Paritsky, Nina Pastukh, Diana Brodsky, Natalya Isakovich, Avi Peretz
Maya Paritsky, Department of Gastroenterology, Baruch Padeh Medical Center, Poria, Lower Galilee 15208, Israel
Nina Pastukh, Diana Brodsky, Natalya Isakovich, Avi Peretz, Clinical Microbiology and Research Laboratory, Baruch Padeh Medical Center, Poria, Affiliated with the Faculty of Medicine, Bar Ilan University, Tiberias 15208, Israel
Author contributions: Paritsky M, Peretz A and Pastukh N contributed equally to this work; Paritsky M and Peretz A designed the research; Paritsky M, Peretz A, Pastukh N, Brodsky D and Isakovich N performed the research; Peretz A and Pastukh N wrote the paper.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Avi Peretz, PhD, Head, Clinical Microbiology and Research Laboratory, Baruch Padeh Medical Center, Poria, Affiliated with the Faculty of Medicine, Bar Ilan University, Hanna Senesh 818/2, Tiberias 15208, Israel. aperetz@poria.health.gov.il
Telephone: +972-4-6652322 Fax: +972-4-6652531
Received: October 17, 2014
Peer-review started: October 19, 2014
First decision: December 11, 2014
Revised: December 22, 2014
Accepted: February 5, 2015
Article in press: February 5, 2015
Published online: May 14, 2015
Processing time: 213 Days and 16.7 Hours
Core Tip

Core tip: Currently, there is no available noninvasive, efficient, predictive tool for screening patients in high-risk populations for the purpose of colonoscopy examination. In this prospective study, we show a clear association between the presence of Streptococcus bovis in colonic suction fluid and findings of malignant tumors and large polyps during colonoscopy examination. Stool samples in different forms can be used as screening material for detection of the population at risk for advanced colorectal lesion. This may be preferable to repeated colonoscopy for surveillance in patients who underwent treatment of advanced colonic lesions by endoscopy or surgery.