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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 28, 2015; 21(12): 3449-3461
Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3449
Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3449
Genome-based nutrition: An intervention strategy for the prevention and treatment of obesity and nonalcoholic steatohepatitis
Sonia Roman, Claudia Ojeda-Granados, Omar Ramos-Lopez, Arturo Panduro, Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara, “Fray Antonio Alcalde”, Guadalajara, Jalisco, Mexico and Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco 44280, Mexico
Author contributions: Roman S performed research, wrote the paper and integrated the final version; Ojeda-Granados C performed research and wrote the paper; Ramos-Lopez O performed research and wrote the paper; Panduro A designed, wrote and critically reviewed the paper; all authors revised and approved the final version.
Conflict-of-interest: No potential conflicts of interest relevant to this article were reported.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Arturo Panduro, MD, PhD, Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara, “Fray Antonio Alcalde”, Guadalajara, Jalisco, Mexico and Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco 44280, Mexico. apanduro@prodigy.net.mx
Telephone: +52-33-36147743 Fax: +52-33-36147743
Received: November 28, 2014
Peer-review started: November 28, 2014
First decision: January 8, 2015
Revised: January 21, 2015
Accepted: February 12, 2015
Article in press: February 13, 2015
Published online: March 28, 2015
Processing time: 122 Days and 11.9 Hours
Peer-review started: November 28, 2014
First decision: January 8, 2015
Revised: January 21, 2015
Accepted: February 12, 2015
Article in press: February 13, 2015
Published online: March 28, 2015
Processing time: 122 Days and 11.9 Hours
Core Tip
Core tip: New intervention strategies for the prevention and management of obesity and associated gastrointestinal diseases are warranted due to their chronic complications. In the era of genomic medicine and nutritional genomics, we are now closer to understanding how unbalanced gene-nutrient interactions are involved in the onset and progression of these diseases. The implementation of regionalized diets based on the genetic ancestry and natural staple food sources of each population may result in better health and nutrition worldwide. Further studies are required to tailor the appropriate diet for each type of population to win the battle against obesity and associated co-morbidities.