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World J Gastroenterol. Feb 14, 2014; 20(6): 1529-1536
Published online Feb 14, 2014. doi: 10.3748/wjg.v20.i6.1529
Published online Feb 14, 2014. doi: 10.3748/wjg.v20.i6.1529
Clinical proteomics identifies potential biomarkers in Helicobacter pylori for gastrointestinal diseases
Chun-Hao Huang, Shyh-Horng Chiou, Quantitative Proteomics Center and Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan
Chun-Hao Huang, Shyh-Horng Chiou, Institute of Biological Chemistry, Academia Sinica, Taipei 115, Taiwan
Author contributions: Huang CH and Chiou SH wrote the paper.
Supported by (in part) Kaohsiung Medical University, Academia Sinica, and the National Science Council, Taipei, Taiwan, No. 96-2311-B-037-005-MY3, No.99-2314-B-037-042, and No. 99-2745-B-037-005 to Chiou SH
Correspondence to: Shyh-Horng Chiou, PhD, Special Chair Professor, Quantitative Proteomics Center and Graduate Institute of Medicine, Kaohsiung Medical University, No.100 Shih-Chuan 1st Road, Kaohsiung 807, Taiwan. shchiou@kmu.edu.tw
Telephone: +886-7-3220377 Fax: +886-7-3133434
Received: September 30, 2013
Revised: November 13, 2013
Accepted: January 6, 2014
Published online: February 14, 2014
Processing time: 141 Days and 8.4 Hours
Revised: November 13, 2013
Accepted: January 6, 2014
Published online: February 14, 2014
Processing time: 141 Days and 8.4 Hours
Core Tip
Core tip: This work aims to review the literature on the application of proteomics methodology for identifying proteins differentially expressed in Helicobacter pylori (H. pylori) under different environmental stresses, resulting in the identification of several biomarkers related to gastrointestinal disorders induced by H. pylori infection.