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World J Gastroenterol. Feb 7, 2014; 20(5): 1238-1247
Published online Feb 7, 2014. doi: 10.3748/wjg.v20.i5.1238
Published online Feb 7, 2014. doi: 10.3748/wjg.v20.i5.1238
Epidemiological studies of migration and environmental risk factors in the inflammatory bowel diseases
Yanna Ko, Rhys Butcher, Rupert W Leong, Concord Hospital, Gastroenterology and Liver Services and The University of New South Wales, Sydney NSW 2139, Australia
Author contributions: Ko Y contributed to this work, performed the literature review and the literature review, and analysed the data; Leong RW designed the research; Ko Y, Butcher R and Leong RW wrote the paper.
Supported by A Career Development Fellowship of the National Health and Medical Research Council of Australia to Leong RW
Correspondence to: Rupert W Leong, MBBS, MD, FRACP, AGAF, Associate Professor, Concord Hospital, Gastroenterology and Liver Services and The University of New South Wales, Level 1 West Hospital Rd, Concord, Sydney NSW 2139, Australia. rupertleong@outlook.com
Telephone: +61-2-97676111 Fax: +61-2-97676767
Received: July 17, 2013
Revised: November 27, 2013
Accepted: January 2, 2014
Published online: February 7, 2014
Processing time: 218 Days and 3.1 Hours
Revised: November 27, 2013
Accepted: January 2, 2014
Published online: February 7, 2014
Processing time: 218 Days and 3.1 Hours
Core Tip
Core tip: Inflammatory bowel diseases (IBD) are well known to involve genetic and environmental risk factors. Cohorts from low IBD prevalence regions migrating to areas of high IBD prevalence are candidates to assess further environmental factors - both protective and promotional. There are few opportunities to identify migratory populations to highlight these effects of environmental risk factors in the development of IBD and to compare first- and second-generation migrants. This review highlights known migratory cohorts and identifies an emerging cohort in Middle Eastern migrants to Australia.