Copyright
©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 28, 2014; 20(36): 13167-13171
Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13167
Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13167
Preoperative high level of D-dimers predicts unresectability of pancreatic head cancer
Adam Durczynski, Piotr Hogendorf, Dariusz Szymanski, Janusz Strzelczyk, Department of General and Transplant Surgery, Medical University of Lodz, 90-153 Lodz, Poland
Anna Kumor, Department of Allergology and Pulmonary Diseases, Medical University of Lodz, 90-153 Lodz, Poland
Piotr Grzelak, Department of Radiology and Diagnostic Imaging, Medical University of Lodz, 90-153 Lodz, Poland
Author contributions: All authors contributed equally to this work.
Supported by Grant from Medical University of Lodz, No 503/8-145-01/503/01
Correspondence to: Adam Durczynski, MD, PhD, Department of General and Transplant Surgery, Medical University of Lodz, Kopcinskiego Street 22, 90-153 Lodz, Poland. durek@retsat1.com.pl
Telephone: +48-42-6776755 Fax: +48-42-6791091
Received: January 29, 2014
Revised: April 14, 2014
Accepted: June 14, 2014
Published online: September 28, 2014
Processing time: 245 Days and 13.8 Hours
Revised: April 14, 2014
Accepted: June 14, 2014
Published online: September 28, 2014
Processing time: 245 Days and 13.8 Hours
Core Tip
Core tip: High D-dimer level in patients with resectable pancreatic head cancer based on preoperative imaging studies predicts that tumor may be considered unresectable due to occult hepatic metastases. However, further multi-center studies are needed on high D-dimers in pancreatic head cancer and preoperative clinical decision making and surgical treatment. If verified, D-dimer testing should be performed in all subjects with pancreatic cancer.