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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 28, 2014; 20(36): 13133-13138
Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13133
Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13133
Small-bowel mucosal injuries in low-dose aspirin users with obscure gastrointestinal bleeding
Junichi Iwamoto, Yoshifumi Saito, Koichi Shimokobe, Akira Honda, Tadashi Ikegami, Yasushi Matsuzaki, Department of Gastroenterology, Tokyo Medical University Ibaraki Medical Center, Ibaraki 300-0395, Japan
Yuji Mizokami, Department of Gastroenterology, University of Tsukuba, Ibaraki 305-8576, Japan
Author contributions: Iwamoto J and Shimokobe K analyzed the clinical data; Mizokami Y, Saito Y, Honda A, Ikegami T and Matsuzaki Y were also involved in editing the manuscript; Iwamoto J designed the study and wrote the manuscript.
Correspondence to: Junichi Iwamoto, MD, PhD, Department of Gastroenterology, Tokyo Medical University Ibaraki Medical Center, 3-20-1 Ami-machi Chuo, Inashiki-gun, Ibaraki 300-0395, Japan. junnki@dg.mbn.or.jp
Telephone: +81-29-8871161 Fax: +81-29-8883463
Received: December 10, 2013
Revised: January 18, 2014
Accepted: June 20, 2014
Published online: September 28, 2014
Processing time: 295 Days and 7.2 Hours
Revised: January 18, 2014
Accepted: June 20, 2014
Published online: September 28, 2014
Processing time: 295 Days and 7.2 Hours
Core Tip
Core tip: The aim of this study is that to clarify the clinical feature of ulcerative or erosive lesion of small intestine in the long-term non-steroidal anti-inflammatory drug (NSAID) users who were examined by capsule endoscopy for obscure gastrointestinal bleeding. The ulcerative lesions were predominantly located in both jejunum and ileum or just in ileum while erosive lesions were predominantly found in both jejunum and ileum or just in jejunum significantly. These findings indicate the possibility that distribution of NSAID-induced small intestinal lesion differ according to the types of mucosal injury.