Retrospective Study
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World J Gastroenterol. Aug 28, 2014; 20(32): 11370-11375
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11370
Gastrointestinal symptoms: A comparison between patients undergoing peritoneal dialysis and hemodialysis
Rui Dong, Zhi-Yong Guo, Jia-Rong Ding, Yang-Yang Zhou, Hao Wu
Rui Dong, Zhi-Yong Guo, Jia-Rong Ding, Yang-Yang Zhou, Hao Wu, Department of Nephrology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
Author contributions: Dong R and Guo ZY designed the study; Dong R performed the majority of the study, collected and analyzed the data, and drafted the article; Ding JR, Zhou YY and Wu H participated in data acquisition; Guo ZY provided vital suggestions and interpretation of data, revised the manuscript critically for important intellectual content and give final approval of the version to be published.
Correspondence to: Zhi-Yong Guo, MD, Professor, Department of Nephrology, Changhai Hospital, Second Military Medical University, No. 168 Changhai Road, Yangpu District, Shanghai 200433, China. drguozhiyong@163.com
Telephone: +86-21-31161412 Fax: +86-21-31161418
Received: February 20, 2014
Revised: April 28, 2014
Accepted: July 11, 2014
Published online: August 28, 2014
Processing time: 189 Days and 20.4 Hours
Core Tip

Core tip: End-stage renal disease patients undergoing dialysis frequently experience gastrointestinal symptoms. In agreement with previous studies, a majority of patients undergoing hemodialysis (HD) and peritoneal dialysis (PD) in the present study reported gastrointestinal symptoms. However, the results indicate that the prevalence and severity of various gastrointestinal symptoms differ between patients undergoing these two dialysis treatments. HD patients had a higher prevalence of and more severe constipation, abdominal pain and diarrhea, whereas PD patients experienced stronger and more frequent reflux and eating dysfunction. Furthermore, a significantly greater number of HD patients presented with more than three gastrointestinal symptoms.