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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 28, 2014; 20(32): 11199-11209
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11199
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11199
MicroRNAs as emerging biomarkers and therapeutic targets for pancreatic cancer
Marion Gayral, Sébastien Jo, Naima Hanoun, Alix Vignolle-Vidoni, Hubert Lulka, Yannick Delpu, Aline Meulle, Marlène Dufresne, Marine Humeau, Maël Chalret du Rieu, Barbara Bournet, Janick Sèlves, Rosine Guimbaud, Nicolas Carrère, Louis Buscail, Jérôme Torrisani, Pierre Cordelier, Cancer Research Center of Toulouse Team 10, UMR INSERM U1037, Université Paul Sabatier, 31100 Toulouse, France
Alix Vignolle-Vidoni, Marine Humeau, Maël Chalret du Rieu, Barbara Bournet, Janick Sèlves, Rosine Guimbaud, Nicolas Carrère, Louis Buscail, Pôle Digestif, Centre Hospitalier Universitaire Toulouse, 31100 Toulouse, France
Author contributions: Gayral M, Jo S, Hanoun N, Vignolle-Vidoni A, Lulka H, Delpu Y, Meulle A, Dufresne M, Humeau M, Chalret du Rieu M, Bournet B, Sèlves J, Guimbaud R, Carrère N, Buscail L, Torrisani J and Cordelier P contributed to the bibliographical review; Gayral M, Torrisani J and Cordelier P wrote the paper.
Correspondence to: Pierre Cordelier, PhD, Cancer Research Center of Toulouse Team 10, UMR INSERM U1037, Université Paul Sabatier, Toulouse Oncopole 1, Avenue Joliot Curie, 31100 Toulouse, France. pierre.cordelier@inserm.fr
Telephone: +33-5-61322404 Fax: +33-5-61322403
Received: October 24, 2013
Revised: March 6, 2014
Accepted: June 13, 2014
Published online: August 28, 2014
Processing time: 308 Days and 18.2 Hours
Revised: March 6, 2014
Accepted: June 13, 2014
Published online: August 28, 2014
Processing time: 308 Days and 18.2 Hours
Core Tip
Core tip: Robust biomarkers and reliable treatments are needed to help alleviate the dismal prognosis of pancreatic cancer. In this review, we will highlight the translational studies demonstrating that microRNAs may soon translate into clinical applications as long-awaited screening tools and therapeutic targets for this cancer.