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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 21, 2014; 20(31): 10864-10875
Published online Aug 21, 2014. doi: 10.3748/wjg.v20.i31.10864
Published online Aug 21, 2014. doi: 10.3748/wjg.v20.i31.10864
Update on imaging of Peutz-Jeghers syndrome
Catherine Tomas, Christine Hoeffel, Department of Radiology, Hôpital Robert Debré, 51092 Reims Cedex, France
Philippe Soyer, Anthony Dohan, Mourad Boudiaf, Department of Abdominal Imaging, Hôpital Lariboisière-AP-HP and Université Diderot Paris 7, 75475 Paris Cedex 10, France
Xavier Dray, Department of Digestive Diseases, Hôpital Lariboisière-AP-HP and Université Diderot-Paris 7, 75475 Paris Cedex 10, France
Author contributions: Guarantors of integrity of entire study by Tomas C and Hoeffel C; Study concepts/study design by Tomas C, Soyer P and Hoeffel C; Data acquisition or data analysis/interpretation by Tomas C, Hoeffel C, Soyer P, Dohan A, Dray X and Boudiaf M; all authors drafting or manuscript revision for important intellectual content, manuscript final version approval; Literature research by Tomas C, Soyer P and Hoeffel C.
Correspondence to: Catherine Tomas, MD, Department of Radiology, Hôpital Robert Debré, 11 Boulevard Pasteur, 51092 Reims Cedex, France. catherine.tomas@hotmail.fr
Telephone: +33-326784216 Fax: +33-3-267884 77
Received: October 30, 2013
Revised: April 3, 2014
Accepted: May 19, 2014
Published online: August 21, 2014
Processing time: 294 Days and 14.7 Hours
Revised: April 3, 2014
Accepted: May 19, 2014
Published online: August 21, 2014
Processing time: 294 Days and 14.7 Hours
Core Tip
Core tip: Peutz-Jeghers syndrome is a rare disease characterized by the development of hamartomatous polyps in the gastrointestinal tract. Patients affected by this syndrome have an increased risk of developing gastrointestinal and extradigestive cancers. Regular small-bowel surveillance is necessary to mitigate this increased risk, and recently developed techniques have an important role in the management of Peutz-Jeghers syndrome. This review illustrates the pathological, clinical and imaging features of small-bowel abnormalities as well as the role and performance of the most recent imaging modalities in the detection and monitoring of small-bowel abnormalities in PJS patients.