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World J Gastroenterol. Jun 28, 2014; 20(24): 7808-7818
Published online Jun 28, 2014. doi: 10.3748/wjg.v20.i24.7808
Published online Jun 28, 2014. doi: 10.3748/wjg.v20.i24.7808
Applications of endoscopic ultrasound in pancreatic cancer
Leticia Perondi Luz, Mohammad Ali Al-Haddad, Michael Sai Lai Sey, John M DeWitt, Division of Gastroenterology and Hepatology, Indiana University, Medical Center, Roudebush VA Medical Center, Indianapolis, IN 46202, United States
Author contributions: All authors contributed equally to the intellectual conception of the manuscript and approved the final version; Luz LP and DeWitt JM performed extensive literature research and drafted the article; AL-Haddad MA and Sey MSL revised the manuscript critically.
Correspondence to: John M DeWitt, MD, Division of Gastroenterology and Hepatology, Indiana University, Medical Center, Roudebush VA Medical Center, 550 N University Blvd., UH 4100, Indianapolis, IN 46202, United States. jodewitt@iupui.edu
Telephone: +1-317-9441113 Fax: +1-317-9488144
Received: November 2, 2013
Revised: January 15, 2014
Accepted: February 16, 2014
Published online: June 28, 2014
Processing time: 241 Days and 10.4 Hours
Revised: January 15, 2014
Accepted: February 16, 2014
Published online: June 28, 2014
Processing time: 241 Days and 10.4 Hours
Core Tip
Core tip: Applications of endoscopic ultrasound (EUS) in pancreatic cancer are emerging. We review the role of EUS in the detection, diagnosis and staging of pancreatic cancer. The introduction of recent novel techniques such as contrast-enhanced EUS, elastography and analysis of DNA markers in fine-needle aspiration samples might improve the accuracy of EUS. In addition, we review therapeutic application of EUS including celiac plexus interventions, fiducial and brachytherapy seeds placement, fine needle injection and EUS-guided biliary drainage.