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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 28, 2014; 20(24): 7696-7706
Published online Jun 28, 2014. doi: 10.3748/wjg.v20.i24.7696
Published online Jun 28, 2014. doi: 10.3748/wjg.v20.i24.7696
Human genes involved in hepatitis B virus infection
Zheng Zeng, Department of Infectious Diseases, Peking University First Hospital, Beijing 100034, China
Author contributions: Zeng Z designed and wrote the manuscript.
Supported by National Cancer Institute, National Institute of Health, USA, No. N01-CO-12400; National Nature Science Foundation of China, No. 30671855; and International Science & Technology Cooperation Program of China, No. 2014DFR31200.
Correspondence to: Zheng Zeng, Professor, Department of Infectious Diseases, Peking University First Hospital, No. 8, Xishiku Street, Xicheng District, Beijing 100034, China. zeng@bjmu.edu.cn
Telephone: +86-10-83572370 Fax: +86-10-66551799
Received: October 28, 2013
Revised: January 10, 2014
Accepted: March 7, 2014
Published online: June 28, 2014
Processing time: 241 Days and 17.4 Hours
Revised: January 10, 2014
Accepted: March 7, 2014
Published online: June 28, 2014
Processing time: 241 Days and 17.4 Hours
Core Tip
Core tip: This manuscript is a review and summary of the advances about human genetic polymorphisms that are associated with hepatitis B virus (HBV) clearance and persistent infection. Especially, large sample size candidate gene association studies and genome-wide association studies, which discovered several gene polymorphisms that are associated with HBV clearance, such as HLA-DPA1 and HLA-DPB1 polymorphisms, are focused.